Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease
Because regional blood flow increases in association with the increased metabolic demand
generated by localised increases in neural activity, functional imaging researchers often …
generated by localised increases in neural activity, functional imaging researchers often …
Pericyte structural remodeling in cerebrovascular health and homeostasis
AA Berthiaume, DA Hartmann, MW Majesky… - Frontiers in aging …, 2018 - frontiersin.org
The biology of brain microvascular pericytes is an active area of research and discovery, as
their interaction with the endothelium is critical for multiple aspects of cerebrovascular …
their interaction with the endothelium is critical for multiple aspects of cerebrovascular …
Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain
Pericytes are perivascular mural cells of brain capillaries. They are positioned centrally in
the neurovascular unit between endothelial cells, astrocytes and neurons. This position …
the neurovascular unit between endothelial cells, astrocytes and neurons. This position …
Diverse functions of pericytes in cerebral blood flow regulation and ischemia
F Fernández-Klett, J Priller - Journal of Cerebral Blood Flow …, 2015 - journals.sagepub.com
Pericytes are mural cells with contractile properties. Here, we provide evidence that
microvascular pericytes modulate cerebral blood flow in response to neuronal activity …
microvascular pericytes modulate cerebral blood flow in response to neuronal activity …
[HTML][HTML] Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
RD Bell, EA Winkler, AP Sagare, I Singh, B LaRue… - Neuron, 2010 - cell.com
Pericytes play a key role in the development of cerebral microcirculation. The exact role of
pericytes in the neurovascular unit in the adult brain and during brain aging remains …
pericytes in the neurovascular unit in the adult brain and during brain aging remains …
Pericytes and neurovascular function in the healthy and diseased brain
Pericytes are multi-functional cells embedded within the walls of capillaries throughout the
body, including the brain. Pericytes were first identified in the 1870s, but little attention was …
body, including the brain. Pericytes were first identified in the 1870s, but little attention was …
Central nervous system pericytes in health and disease
EA Winkler, RD Bell, BV Zlokovic - Nature neuroscience, 2011 - nature.com
Pericytes are uniquely positioned within the neurovascular unit to serve as vital integrators,
coordinators and effectors of many neurovascular functions, including angiogenesis, blood …
coordinators and effectors of many neurovascular functions, including angiogenesis, blood …
Imaging pericytes and capillary diameter in brain slices and isolated retinae
The cerebral circulation is highly specialized, both structurally and functionally, and it
provides a fine-tuned supply of oxygen and nutrients to active regions of the brain. Our …
provides a fine-tuned supply of oxygen and nutrients to active regions of the brain. Our …
Pericyte control of blood flow across microvascular zones in the central nervous system
DA Hartmann, V Coelho-Santos… - Annual review of …, 2022 - annualreviews.org
The vast majority of the brain's vascular length is composed of capillaries, where our
understanding of blood flow control remains incomplete. This review synthesizes current …
understanding of blood flow control remains incomplete. This review synthesizes current …
Brain microvascular pericytes in health and disease
T Dalkara, Y Gursoy-Ozdemir, M Yemisci - Acta neuropathologica, 2011 - Springer
Pericytes are located at periphery of the microvessel wall and wrap it with their processes.
They communicate with other cells of the neurovascular unit by direct contact or through …
They communicate with other cells of the neurovascular unit by direct contact or through …