Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease

NB Hamilton, D Attwell, CN Hall - Frontiers in neuroenergetics, 2010 - frontiersin.org
Because regional blood flow increases in association with the increased metabolic demand
generated by localised increases in neural activity, functional imaging researchers often …

Pericyte structural remodeling in cerebrovascular health and homeostasis

AA Berthiaume, DA Hartmann, MW Majesky… - Frontiers in aging …, 2018 - frontiersin.org
The biology of brain microvascular pericytes is an active area of research and discovery, as
their interaction with the endothelium is critical for multiple aspects of cerebrovascular …

Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain

K Kisler, AR Nelson, SV Rege, A Ramanathan… - Nature …, 2017 - nature.com
Pericytes are perivascular mural cells of brain capillaries. They are positioned centrally in
the neurovascular unit between endothelial cells, astrocytes and neurons. This position …

Diverse functions of pericytes in cerebral blood flow regulation and ischemia

F Fernández-Klett, J Priller - Journal of Cerebral Blood Flow …, 2015 - journals.sagepub.com
Pericytes are mural cells with contractile properties. Here, we provide evidence that
microvascular pericytes modulate cerebral blood flow in response to neuronal activity …

[HTML][HTML] Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

RD Bell, EA Winkler, AP Sagare, I Singh, B LaRue… - Neuron, 2010 - cell.com
Pericytes play a key role in the development of cerebral microcirculation. The exact role of
pericytes in the neurovascular unit in the adult brain and during brain aging remains …

Pericytes and neurovascular function in the healthy and diseased brain

LS Brown, CG Foster, JM Courtney, NE King… - Frontiers in cellular …, 2019 - frontiersin.org
Pericytes are multi-functional cells embedded within the walls of capillaries throughout the
body, including the brain. Pericytes were first identified in the 1870s, but little attention was …

Central nervous system pericytes in health and disease

EA Winkler, RD Bell, BV Zlokovic - Nature neuroscience, 2011 - nature.com
Pericytes are uniquely positioned within the neurovascular unit to serve as vital integrators,
coordinators and effectors of many neurovascular functions, including angiogenesis, blood …

Imaging pericytes and capillary diameter in brain slices and isolated retinae

A Mishra, FM O'farrell, C Reynell, NB Hamilton… - Nature protocols, 2014 - nature.com
The cerebral circulation is highly specialized, both structurally and functionally, and it
provides a fine-tuned supply of oxygen and nutrients to active regions of the brain. Our …

Pericyte control of blood flow across microvascular zones in the central nervous system

DA Hartmann, V Coelho-Santos… - Annual review of …, 2022 - annualreviews.org
The vast majority of the brain's vascular length is composed of capillaries, where our
understanding of blood flow control remains incomplete. This review synthesizes current …

Brain microvascular pericytes in health and disease

T Dalkara, Y Gursoy-Ozdemir, M Yemisci - Acta neuropathologica, 2011 - Springer
Pericytes are located at periphery of the microvessel wall and wrap it with their processes.
They communicate with other cells of the neurovascular unit by direct contact or through …