High-amplitude cofluctuations in cortical activity drive functional connectivity

F Zamani Esfahlani, Y Jo, J Faskowitz… - Proceedings of the …, 2020 - National Acad Sciences
Resting-state functional connectivity is used throughout neuroscience to study brain
organization and to generate biomarkers of development, disease, and cognition. The …

Individualized event structure drives individual differences in whole-brain functional connectivity

RF Betzel, SA Cutts, S Greenwell, J Faskowitz… - NeuroImage, 2022 - Elsevier
Resting-state functional connectivity is typically modeled as the correlation structure of
whole-brain regional activity. It is studied widely, both to gain insight into the brain's intrinsic …

Modular origins of high-amplitude cofluctuations in fine-scale functional connectivity dynamics

M Pope, M Fukushima, RF Betzel… - Proceedings of the …, 2021 - National Acad Sciences
The topology of structural brain networks shapes brain dynamics, including the correlation
structure of brain activity (functional connectivity) as estimated from functional neuroimaging …

Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations

G Deco, A Ponce-Alvarez, D Mantini… - Journal of …, 2013 - Soc Neuroscience
Brain fluctuations at rest are not random but are structured in spatial patterns of correlated
activity across different brain areas. The question of how resting-state functional connectivity …

Principal components of functional connectivity: a new approach to study dynamic brain connectivity during rest

N Leonardi, J Richiardi, M Gschwind, S Simioni… - NeuroImage, 2013 - Elsevier
Functional connectivity (FC) as measured by correlation between fMRI BOLD time courses
of distinct brain regions has revealed meaningful organization of spontaneous fluctuations in …

Network-level structure-function relationships in human neocortex

B Mišić, RF Betzel, MA De Reus… - Cerebral …, 2016 - academic.oup.com
The dynamics of spontaneous fluctuations in neural activity are shaped by underlying
patterns of anatomical connectivity. While numerous studies have demonstrated edge-wise …

[HTML][HTML] Temporal fluctuations in the brain's modular architecture during movie-watching

RF Betzel, L Byrge, FZ Esfahlani, DP Kennedy - Neuroimage, 2020 - Elsevier
Brain networks are flexible and reconfigure over time to support ongoing cognitive
processes. However, tracking statistically meaningful reconfigurations across time has …

BOLD cofluctuation 'events' are predicted from static functional connectivity

Z Ladwig, BA Seitzman, A Dworetsky, Y Yu… - NeuroImage, 2022 - Elsevier
Recent work identified single time points (“events”) of high regional cofluctuation in
functional Magnetic Resonance Imaging (fMRI) which contain more large-scale brain …

Dynamic fluctuations coincide with periods of high and low modularity in resting-state functional brain networks

RF Betzel, M Fukushima, Y He, XN Zuo, O Sporns - NeuroImage, 2016 - Elsevier
We investigate the relationship of resting-state fMRI functional connectivity estimated over
long periods of time with time-varying functional connectivity estimated over shorter time …

Time-resolved structure-function coupling in brain networks

ZQ Liu, B Vazquez-Rodriguez, RN Spreng… - Communications …, 2022 - nature.com
The relationship between structural and functional connectivity in the brain is a key question
in systems neuroscience. Modern accounts assume a single global structure-function …