The apoAI-CIII-AIV gene cluster

M Groenendijk, RM Cantor, TWA de Bruin… - Atherosclerosis, 2001 - Elsevier
The relationship between variations in the apoAI-CIII-AIV gene cluster and plasma lipid traits
has been recognized for at least 15 years. Most studies have been focused upon the …

Genetic markers in the apo AI-CIII-AIV gene cluster for combined hyperlipidemia, hypertriglyceridemia, and predisposition to atherosclerosis

A Tybjærg-Hansen, BG Nordestgaard, LU Gerdes… - Atherosclerosis, 1993 - Elsevier
The aim of the present study was to search for genetic determinants of combined
hyperlipidemia and hypertriglyceridemia, and to evaluate whether such determinants might …

Polymorphisms in the apolipoprotein (apo) AI-CIII-AIV gene cluster: detection of genetic variation determining plasma apo AI, apo CIII and apo AIV concentrations

H Paul-Hayase, M Rosseneu, D Robinson… - Human genetics, 1992 - Springer
We have examined the associations between levels of plasma apolipoprotein (apo) AI, apo
CIII and apo AIV and genetic variation in the apo AI-CIII-AIV gene cluster in 162 boys and …

Genetic variation in the apolipoprotein AI-CIII-AIV gene cluster and coronary heart disease

B Paulweber, W Friedl, F Krempler, SE Humphrie… - Atherosclerosis, 1988 - Elsevier
Six RFLPs in the apolipoprotein (apo) AI-CIII-AIV gene region detected with the restriction
enzymes XmnI, MspI, PstI, SstI and PμuII were used to study the role of genetic variation at …

Variation at the apo AI/CIII/A1V gene complex is associated with elevated plasma levels of apo CIII

CC Shoulders, PJ Harry, L Lagrost, SE White, NF Shah… - Atherosclerosis, 1991 - Elsevier
A number of studies have reported that a variant allele (S2) of the apo AI/CIII/AIV complex is
associated with high plasma lipid levels in some populations and furthermore that the …

Associations of genotypes at the apolipoprotein AI‐CIII‐AIV, apolipoprotein B and lipoprotein lipase gene loci with coronary atherosclerosis and high density …

RE Peacock, A Hamsten, J Johansson… - Clinical …, 1994 - Wiley Online Library
Association studies were carried out in a sample of 86 patients from Sweden who had
survived a myocardial infarction (MI) at a young age and 93 age‐matched healthy …

Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia

AP Surguchov, GP Page, L Smith… - … , and vascular biology, 1996 - Am Heart Assoc
Hypertriglyceridemia and hyperlipidemia are common disorders associated with coronary
artery disease and premature death. The proteins encoded by the apolipoprotein (apo) AI/C …

Restriction fragment length polymorphisms of the apolipoprotein AI, C-III, A-IV gene locus Relationships with lipids, apolipoproteins, and premature coronary artery …

JM Ordovas, F Civeira, J Genest Jr, S Craig… - Atherosclerosis, 1991 - Elsevier
Data from various laboratories have indicated associations of various alleles determined by
RFLPs within or adjacent to several apolipoprotein genes with abnormalities in plasma …

Lack of association between genetic variations of apo AI–C-III–A-IV gene cluster and myocardial infarction in a sample of European male: ECTIM study

F Kee, P Amouyel, F Fumeron, D Arveiler, JP Cambou… - Atherosclerosis, 1999 - Elsevier
The goal of the present study was to compare the allele frequency of four polymorphisms at
the apo AI C-III A-IV cluster gene locus—ApoA-I: XmnI and PstI; ApoC-III: SstI; ApoA-IV: XbaI …

Association between genetic variation at the APO AI‐CIII‐AIV gene cluster and familial combined hyperlipidaemia

CF Xu, P Talmud, H Schuster, R Houlston… - Clinical …, 1994 - Wiley Online Library
By using chemical cleavage mismatch analysis and the single strand conformation
polymorphism technique, DNA fragments of the apo CIII gene, including the 5′ flanking …