The Zone model of pulmonary perfusion predicts that exercise reduces perfusion
heterogeneity because increased vascular pressure redistributes flow to gravitationally …

Ventilation-perfusion matching occurs passively and is also actively regulated through
hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly …

Exercise presents a considerable stress to the pulmonary system and ventilation-perfusion
(V̇a/Q̇) heterogeneity increases with exercise, affecting the efficiency of gas exchange. In …

Heavy exercise increases ventilation-perfusion mismatch and decreases pulmonary gas
exchange efficiency. Previous work using magnetic resonance imaging (MRI) arterial spin …

Purpose: To evaluate the performance of lung perfusion imaging using two‐dimensional
(2D) first pass perfusion MRI and a quantitation program based on model‐independent …

We have developed a novel functional proton magnetic resonance imaging (MRI) technique
to measure regional ventilation-perfusion (V̇A/Q̇) ratio in the lung. We conducted a …

The gravitational gradient of intrapleural pressure is suggested to be less in prone posture
than supine. Thus the gravitational distribution of ventilation is expected to be more uniform …

Key points Pulmonary perfusion measurement using magnetic resonance imaging
combined with deformable image registration enabled us to quantify the change in the …

We hypothesized that some of the heterogeneity of pulmonary blood flow present in the
normal human lung in normoxia is due to hypoxic pulmonary vasoconstriction (HPV). If so …

Normal aging is associated with a decline in pulmonary function and efficiency of gas
exchange, although the effects on the spatial distribution of pulmonary perfusion are poorly …