Sepsis calculator implementation reduces empiric antibiotics for suspected early-onset sepsis

NB Achten, JW Dorigo-Zetsma… - European journal of …, 2018 - Springer
Significant overtreatment with antibiotics for suspected early onset sepsis (EOS) constitutes
a persisting clinical problem, generating unnecessary risks, harms, and costs for many …

[HTML][HTML] Stratification of culture-proven early-onset sepsis cases by the neonatal early-onset sepsis calculator: an individual patient data meta-analysis

NB Achten, FB Plötz, C Klingenberg, M Stocker… - The Journal of …, 2021 - Elsevier
Objectives To provide a comprehensive assessment of case stratification by the Neonatal
Early-Onset Sepsis (EOS) Calculator, a novel tool for reducing unnecessary antibiotic …

Association of use of the neonatal early-onset sepsis calculator with reduction in antibiotic therapy and safety: a systematic review and meta-analysis

NB Achten, C Klingenberg, WE Benitz… - JAMA …, 2019 - jamanetwork.com
Importance The neonatal early-onset sepsis (EOS) calculator is a clinical risk stratification
tool increasingly used to guide the use of empirical antibiotics for newborns. Evidence on …

Application of sepsis calculator in newborns with suspected infection

M Kerste, J Corver, MC Sonnevelt… - The Journal of …, 2016 - Taylor & Francis
Objective: To compare actual antibiotic use to the stratification based on the sepsis
calculator in newborns with suspected early onset sepsis (EOS). To investigate differences …

Impact of neonatal early-onset sepsis calculator on antibiotic use within two tertiary healthcare centers

S Warren, M Garcia, C Hankins - Journal of Perinatology, 2017 - nature.com
Objective: A recently described neonatal early-onset sepsis (EOS) calculator has the
potential to reduce newborn antibiotic exposure but real world data from its use remains …

Implementation of the neonatal sepsis calculator in an Australian tertiary perinatal centre

T Strunk, A Buchiboyina, M Sharp, E Nathan, D Doherty… - Neonatology, 2018 - karger.com
Background: Early-onset sepsis (EOS) is a potentially fatal condition that affects about 0.3–
0.8/1,000 infants born at≥ 35 weeks' gestation in developed countries. Current EOS …

[HTML][HTML] Early onset sepsis calculator implementation is associated with reduced healthcare utilization and financial costs in late preterm and term newborns

NB Achten, DH Visser, E Tromp, W Groot… - European journal of …, 2020 - Springer
The neonatal early onset sepsis (EOS) calculator is a novel tool for antibiotic stewardship in
newborns, associated with a reduction of empiric antibiotic treatment for suspected EOS. We …

Sepsis calculator for neonatal early onset sepsis–a systematic review and meta-analysis

M Deshmukh, S Mehta, S Patole - The Journal of Maternal-Fetal & …, 2021 - Taylor & Francis
Background Over investigation and overuse of empirical antibiotics is a concern in
management of neonatal early onset sepsis (EOS) using the Centers for Disease Control …

Variation in current management of term and late-preterm neonates at risk for early-onset sepsis: an international survey and review of guidelines

W Van Herk, S El Helou, J Janota… - The Pediatric …, 2016 - journals.lww.com
Background: Uncertainty about the presence of infection results in unnecessary and
prolonged empiric antibiotic treatment of newborns at risk for early-onset sepsis (EOS). This …

Comparison of the management recommendations of the Kaiser Permanente neonatal early-onset sepsis risk calculator (SRC) with NICE guideline CG149 in infants …

R Morris, S Jones, S Banerjee, A Collinson… - Archives of Disease in …, 2020 - fn.bmj.com
Objective To compare the management recommendations of the Kaiser Permanente
neonatal early-onset sepsis risk calculator (SRC) with National Institute for Health and Care …