Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …

Autophagosome biogenesis involves de novo formation of a membrane that elongates to
sequester cytoplasmic cargo and closes to form a double-membrane vesicle (an …

Autophagy is a bulk degradation system induced by cellular stresses such as nutrient
starvation. Its function relies on the formation of double-membrane vesicles called …

Autophagy is a unique form of membrane trafficking, which delivers macromolecules and
organelles from the cytoplasm to lysosomes for degradation. This fundamental and …

Autophagy is a lysosome-mediated degradative system that is a highly conserved pathway
present in all eukaryotes. In all cells, double-membrane autophagosomes form and engulf …

Autophagy is the main cellular catabolic process responsible for degrading organelles and
large protein aggregates. It is initiated by the formation of a unique membrane structure, the …

Autophagy is a unique membrane trafficking process whereby newly formed membranes,
termed phagophores, engulf parts of the cytoplasm leading to the production of double …

Autophagy is a major catabolic pathway in eukaryotes, which is required for the
lysosomal/vacuolar degradation of cytoplasmic proteins and organelles. Interest in the …

Autophagy is an evolutionarily conserved multistep degradation mechanism in eukaryotes,
that maintains cellular homoeostasis by replenishing cells with nutrients through catabolic …

Autophagy is a degradation process accompanied by dynamic membrane organization. In
the yeast, Saccharomyces cerevisiae, about 30 ATG (autophagy-related) genes have been …