Muscle wasting and cachexia in heart failure: mechanisms and therapies

S Von Haehling, N Ebner, MR Dos Santos… - Nature Reviews …, 2017 - nature.com
Body wasting is a serious complication that affects a large proportion of patients with heart
failure. Muscle wasting, also known as sarcopenia, is the loss of muscle mass and strength …

Sarcopenia, cachexia, and muscle performance in heart failure: Review update 2016

M Saitoh, J Ishida, W Doehner, S von Haehling… - International journal of …, 2017 - Elsevier
Cachexia in the context of heart failure (HF) has been termed cardiac cachexia, and
represents a progressive involuntary weight loss. Cachexia is mainly the result of an …

Muscle wasting in cardiac cachexia

S Strassburg, J Springer, SD Anker - … journal of biochemistry & cell biology, 2005 - Elsevier
Cardiac cachexia is a serious complication of chronic heart failure which is characterized by
complex changes that overall lead to a catabolic/anabolic imbalance resulting in body …

The wasting continuum in heart failure: from sarcopenia to cachexia

S von Haehling - Proceedings of the Nutrition Society, 2015 - cambridge.org
Sarcopenia (muscle wasting) and cachexia share some pathophysiological aspects.
Sarcopenia affects approximately 20%, cachexia< 10% of ambulatory patients with heart …

Cachexia, muscle wasting, and frailty in cardiovascular disease

A Bielecka‐Dabrowa, N Ebner… - European journal of …, 2020 - Wiley Online Library
The last several years have seen increasing interest in understanding cachexia, muscle
wasting, and physical frailty across the broad spectrum of patients with cardiovascular …

Muscle wasting in heart failure: an overview

S von Haehling, L Steinbeck, W Doehner… - The international journal …, 2013 - Elsevier
Patients with heart failure are frequently limited in their exercise capacity. Although this
clinical phenomenon is mostly attributed to the failing myocardium, the effects of skeletal …

Pathophysiology of peripheral muscle wasting in cardiac cachexia

GS Filippatos, SD Anker… - Current Opinion in …, 2005 - journals.lww.com
Many hypotheses have been used to explain the pathogenesis of muscle wasting in cardiac
cachexia. Cardiac cachexia is a multifactorial disorder, and the targeting of different …

Cardiac cachexia: a well-known but challenging complication of heart failure

H Krysztofiak, M Wleklik, J Migaj, M Dudek… - … interventions in aging, 2020 - Taylor & Francis
Heart failure (HF) is a common complication of various cardiac diseases, and its incidence
constantly increases. This is caused mainly by aging of populations and improvement in the …

Cardiac cachexia: hic et nunc

G Loncar, J Springer, M Anker… - Journal of cachexia …, 2016 - Wiley Online Library
Cardiac cachexia (CC) is the clinical entity at the end of the chronic natural course of heart
failure (HF). Despite the efforts, even the most recent definition of cardiac cachexia has been …

[HTML][HTML] Muscle wasting and sarcopenia in heart failure—the current state of science

A Lena, MS Anker, J Springer - International journal of molecular sciences, 2020 - mdpi.com
Sarcopenia is primarily characterized by skeletal muscle disturbances such as loss of
muscle mass, quality, strength, and physical performance. It is commonly seen in elderly …