[HTML][HTML] Immunomodulatory function of vitamin D and its role in autoimmune thyroid disease

R Zhao, W Zhang, C Ma, Y Zhao, R Xiong… - Frontiers in …, 2021 - frontiersin.org
Vitamin D is one of the most important nutrients required by the human body. It is a steroid
hormone that plays an important role in regulating calcium and phosphorus metabolism, and …

Vitamin D and autoimmune thyroid diseases: facts and unresolved questions

G Bizzaro, Y Shoenfeld - Immunologic research, 2015 - Springer
Vitamin D deficiency (levels lower than 20 ng/ml) is becoming a global health problem, since
it is increasingly represented even among healthy subjects. Vitamin D, as an environmental …

Immunomodulatory effect of vitamin D and its potential role in the prevention and treatment of thyroid autoimmunity: a narrative review

D Gallo, L Mortara, MB Gariboldi, SAM Cattaneo… - Journal of …, 2020 - Springer
The main role of vitamin D is to control mineral homeostasis. However, recent studies
suggested the existence of a number of extraskeletal effects. Among the latter, preclinical …

[HTML][HTML] Immunomodulatory effects of vitamin D in thyroid diseases

C Mele, M Caputo, A Bisceglia, MT Samà, M Zavattaro… - Nutrients, 2020 - mdpi.com
Vitamin D is a secosteroid with a pleiotropic role in multiple physiological processes.
Besides the well-known activity on bone homeostasis, recent studies suggested a peculiar …

[HTML][HTML] Vitamin D and autoimmune thyroid disease—cause, consequence, or a vicious cycle?

IH Vieira, D Rodrigues, I Paiva - Nutrients, 2020 - mdpi.com
Vitamin D is a steroid hormone traditionally connected to phosphocalcium metabolism. The
discovery of pleiotropic expression of its receptor and of the enzymes involved in its …

Vitamin D and autoimmune thyroid diseases

S Kivity, N Agmon-Levin, M Zisappl, Y Shapira… - Cellular & molecular …, 2011 - nature.com
The role of vitamin D as an immune modulator has been emphasized in recent years, and
low levels of the hormone were observed in several autoimmune diseases including …

Emerging role of vitamin D in autoimmune diseases: An update on evidence and therapeutic implications

G Murdaca, A Tonacci, S Negrini, M Greco, M Borro… - Autoimmunity …, 2019 - Elsevier
Vitamin D plays a key role in in calcium homeostasis and, thus, provides an important
support in bone growth by aiding in the mineralization of the collagen matrix. However …

Does vitamin D play a role in autoimmune endocrine disorders? A proof of concept

B Altieri, G Muscogiuri, L Barrea, C Mathieu… - Reviews in Endocrine …, 2017 - Springer
In the last few years, more attention has been given to the “non-calcemic” effect of vitamin D.
Several observational studies and meta-analyses demonstrated an association between …

[HTML][HTML] Pathophysiological role and therapeutic implications of vitamin D in autoimmunity: focus on chronic autoimmune diseases

M Bellan, L Andreoli, C Mele, PP Sainaghi… - Nutrients, 2020 - mdpi.com
Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology.
Besides the canonical regulatory activity on bone metabolism, several non-classical actions …

[HTML][HTML] The role of vitamin D in thyroid diseases

D Kim - International journal of molecular sciences, 2017 - mdpi.com
The main role of vitamin D is regulating bone metabolism and calcium and phosphorus
homeostasis. Over the past few decades, the importance of vitamin D in non-skeletal actions …