Primary objective: To review the neural circuitry and neurochemistry of working memory and
outline the evidence for working memory deficits after traumatic brain injury, and the …

Pharmacotherapy may contribute to the rehabilitation of persons with posttraumatic cognitive
impairments. This article reviews first the neurobiological consequences of traumatic brain …

Cognitive problems are one of the main causes of ongoing disability after traumatic brain
injury. The heterogeneity of the injuries sustained and the variability of the resulting …

Cognitive complaints are a frequent source of distress and disability after mild and moderate
traumatic brain injury (TBI). While there are deficits in several cognitive domains, many …

Opinion statement• Cognitive impairment is a common consequence of traumatic brain
injury (TBI) and a substantial source of disability. Across all levels of TBI severity, attention …

Alterations in working memory (WM) are common after traumatic brain injury (TBI). Frontal
catecholaminergic systems, including the alpha-2 adrenergic system, modulate WM function …

Among the many pathophysiologic consequences of traumatic brain injury are changes in
catecholamines, including dopamine, epinephrine, and norepinephrine. In the context of …

Cognitive deficits are an extremely common consequence of either traumatic brain injury or
stroke. Recent studies demonstrate the potential for using neuropharmacological …

Traumatic brain injury (TBI) often results in cognitive impairments for patients. The aim of this
proof of concept study was to establish the nature of abnormalities, in terms of activity and …

Catecholamines, particularly dopamine, modulate working memory (WM). Altered sensitivity
to dopamine might play a role in WM changes observed after traumatic brain injury (TBI) …