In this study, we have investigated the cellular and molecular basis for immunoregulatory
function of T4+ cells after autologous mixed lymphocyte reaction (AMLR) activation. We …

It is suggested that autologous mixed lymphocyte reaction (AMLR) may play an important
role in generating suppressor inducer signals and in down-regulating the immune response …

We examined the nature of an autologous mixed lymphocyte reaction (AMLR) using T cell
subsets defined by monoclonal antibodies. Cells capable of proliferating in the AMLR were …

The monoclonal antibody anti‐2H4 recognizes a 220‐kDa and 200‐kDa glycoprotein and
subdivides T4+ cells into distinct subpopulations: the T4+ 2H4+ inducer of suppression and …

To understand further the biologic significance of the autologous mixed lymphocyte reaction,
we determined the functional properties of autoreactive T cell lines and clones. Initially, we …

The immune response of T cells to self-HLA antigens on autologous non-T cells is known as
the autologous mixed lymphocyte reaction (AMLR), and is defective in various diseases. We …

Specific suppressor T cells (Ts) were induced in vitro by incubation of mouse spleen/lymph
node cells with allogeneic heat‐treated cells. These Ts inhibit mixed lymphocyte reaction …

It has been demonstrated that the T4+ 2H4+ subset functioned as a suppressor inducer cell,
whereas the reciprocal T4+ 2H4-subset provided help for B cell Ig production. In the present …

The role of non-H-2 alloantigens, specifically Mls locus products, in secondary in vitro T-cell-
mediated cytotoxicity has been studied. Splenic T lymphocytes, activated against Mls locus …

Previous studies demonstrated that patients with active systemic lupus erythematosus (SLE),
especially those with active renal disease, had a marked reduction in T4+ 2H4+ suppressor …