A wound is damage of a tissue usually caused by laceration of a membrane, generally the
skin. Wound healing is accomplished in three stages in healthy individuals, including …

Between 1 and 2% of the population in the developed world experiences a nonhealing or
chronic wound characterized by an apparent arrest in a stage dominated by inflammatory …

Background Chronic wound pathogenic biofilms are host-pathogen environments that
colonize and exist as a cohabitation of many bacterial species. These bacterial populations …

Chronic wounds contain complex polymicrobial communities of sessile organisms that have
been underappreciated because of limitations of standard culture techniques. The aim of …

Microbial imbalances and synergistic relationships between bacteria in medically important
biofilms are poorly researched. Consequently, little is known about how synergy between …

Chronic wounds represent an important burden on the healthcare system, requiring frequent
hospitalizations and expensive treatments. It is now recognized that a primary factor …

Chronic wounds represent a large and growing disease burden. Infection and biofilm
formation are two of the leading impediments of wound healing, suggesting an important …

Bacterial colonization occurs in all wounds, chronic or acute, and the break in epithelium
integrity that defines a wound impairs the forces that shape and constrain the microbiome at …

Chronic wounds expose the dermal matrix and underlying tissue to a diversity of microbes
from the body and surrounding environment. We determined the microbial diversity of 19 …

An appreciation of the factors affecting the progression from colonization to infection can
help clinicians with the interpretation of clinical findings and microbiological investigations in …