We have previously described serine amide phosphates (SAPs) as a novel class of cytotoxic
agents for prostate cancer. Several of them showed potent cytotoxicity against human …

To improve the selectivity and antiproliferative activity of previously reported serine amide
phosphates (SAPs), we designed a new series of 4-thiazolidinone amides, in which the 4 …

A series of (2RS, 4R)-2-arylthiazolidine-4-carboxylic acid amide (ATCAA) was synthesized.
Antiproliferative activity against melanoma and prostate cancer cells compared with control …

We have previously described 2-aryl-thiazolidine-4-carboxylic acid amides as a novel class
of antiproliferative agents for prostate cancer. Screening these compounds with melanoma …

To discover novel anticancer agents with potent and low toxicity, we designed and
synthesized a range of new thiosemicarbazone-indole analogues based on lead compound …

We report the SAR studies of 43 ionone-based chalcones that demonstrate substantial in
vitro anti-proliferative activities in LNCaP, MDA-PCa-2b, 22Rv1, C4-2B and PC-3 prostate …

A series of novel thiourea α-aminophosphonate derivatives containing DHA structure was
designed and synthesized as antitumor agents. Their inhibitory activities against the NCI …

A series of anilino substituted pyrimidine sulfonamides were prepared and evaluated for
their anticancer activity. These sulfonamides showed promising activity with IC50 values …

Abstract Two series of thieno [2, 3-d] pyrimidine derivatives were designed and synthesized,
in which bioactive α-aminophosphonate subunits were introduced at the N3 position through …

ABSTRACT Sixteen new 2-(benzothiazol-2-ylthio)-N′-(3-substituted-4-(3, 4-
substitutedphenyl) thiazol-2 (3H)-ylidene) acetohydrazide derivatives (4a-4p) were …