Exocellulr Toxic Factors Prowced by Vibrio Vulnificus

S Miyoshi, EG Oh, K Hirata… - Journal of Toxicology …, 1993 - Taylor & Francis
Vibrio vulnificus is an opportunistic human pathogen causing septicemia or wound-
infections characterized by the formation of edema, necrotic ulcer and cellulitis on the skin …

Bacterial proteases as pathogenic factors, with special emphasis on Vibrio proteases

S Shinoda, SI Miyoshi, H Wakae… - Journal of Toxicology …, 1996 - Taylor & Francis
Bacterial proteases play various pathogenic roles in infection. Pathogenic species of the
genus Vibrio, such as V. cholerae, V. parahaemolyticus or V. vulnificus also produce …

Purification and characterization of an extracellular cytolysin produced by Vibrio vulnificus

LD Gray, AS Kreger - Infection and immunity, 1985 - Am Soc Microbiol
An extracellular cytolytic toxin produced by the halophilic bacterium Vibrio vulnificus was
isolated free of detectable contamination with medium constituents and other bacterial …

Purification and characterization of a hemolysin produced by Vibrio mimicus

S Miyoshi, K Sasahara, S Akamatsu… - Infection and …, 1997 - Am Soc Microbiol
Vibrio mimicus is a causative agent of human gastroenteritis. This pathogen secretes a pore-
forming toxin, V. mimicus hemolysin (VMH), which causes hemolysis by three sequential …

The crucial amino acid residue related to inactivation of Vibrio vulnificus hemolysin

M Senoh, Y Okita, S Shinoda, S Miyoshi - Microbial pathogenesis, 2008 - Elsevier
Vibrio vulnificus, an opportunistic human pathogen causing fetal septicemia, produces a 50-
kDa pore-forming toxin as a virulence factor. This toxin consists of 451 amino acid residues; …

Production of Vibrio vulnificus hemolysin in vivo and its pathogenic significance

SE Lee, PY Ryu, SY Kim, YR Kim, JT Koh… - Biochemical and …, 2004 - Elsevier
Hemolyin/cytolysin (VvhA) is one of the representative exotoxins produced by Vibrio
vulnificus. Cytotoxic mechanism of VvhA has been extensively studied. However, there have …

Vibrio vulnificus may produce a metalloprotease causing an edematous skin lesion in vivo

S Miyoshi, Y Hirata, K Tomochika… - FEMS microbiology …, 1994 - academic.oup.com
Vibrio vulnificus, an opportunistic human pathogen, secretes a metalloprotease which has
been suspected of being the causative factor for edematous skin lesions. The antibody …

Mouse Skin Damage Caused by Cytolysin from Vibrio vulniflcus and by V. vulnificus Infection

LD Gray, AS Kreger - Journal of Infectious Diseases, 1987 - academic.oup.com
Light and electron microscopy of mouse skin damage caused by intradermal infection with a
virulent strain of Vibrio vulnificus and by a single intradermal injection of the cytolytic toxin …

Detection of extracellular toxin (s) produced by Vibrio vulnificus

A Kreger, D Lockwood - Infection and immunity, 1981 - Am Soc Microbiol
Conditions are described for the production, in high titers, a heat-labile, antigenic,
extracellular toxin (s) by Vibrio vulnificus, a recently recognized human pathogen …

[25] Cytolytic toxins of Vibrio vulnificus and Vibrio damsela

AS Kreger, MH Kothary, LD Gray - Methods in Enzymology, 1988 - Elsevier
Publisher Summary This chapter describes the cytolytic toxins of Vibrio vulnificus and Vibrio
damsela. Prior to 1976, Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio alginolyticus …