Role of GABA in anxiety and depression
AV Kalueff, DJ Nutt - Depression and anxiety, 2007 - Wiley Online Library
This review assesses the parallel data on the role of gamma‐aminobutyric acid (GABA) in
depression and anxiety. We review historical and new data from both animal and human …
depression and anxiety. We review historical and new data from both animal and human …
Role of GABA in memory and anxiety
This review assesses the parallel literature on the role of gamma‐aminobutyric acid (GABA)
in memory and anxiety. We review historical and new data from both animal and human …
in memory and anxiety. We review historical and new data from both animal and human …
GABA and mood disorders: a brief review and hypothesis
F Petty - Journal of affective disorders, 1995 - Elsevier
Considerable evidence implicates the neurotransmitter γ-aminobutyric acid (GABA) in the
biochemical pathophysiology of mood disorders. Animal models of depression show …
biochemical pathophysiology of mood disorders. Animal models of depression show …
GABAB receptors and depression: current status
JF Cryan, DA Slattery - Advances in pharmacology, 2010 - Elsevier
Dysfunction of the gamma amino butyric acid (GABA)-ergic system has been purported to
play a role in psychiatric disorders, including anxiety and major depression. A clear link …
play a role in psychiatric disorders, including anxiety and major depression. A clear link …
GABAergic dysfunction in mood disorders
P Brambilla, J Perez, F Barale, G Schettini… - Molecular …, 2003 - nature.com
The authors review the available literature on the preclinical and clinical studies involving
GABAergic neurotransmission in mood disorders. γ-Aminobutyric acid (GABA) is an …
GABAergic neurotransmission in mood disorders. γ-Aminobutyric acid (GABA) is an …
The role of GABA in the pathophysiology and treatment of anxiety disorders.
CB Nemeroff - Psychopharmacology bulletin, 2003 - europepmc.org
Mechanisms underlying the pathological characteristics of the various anxiety disorders
have yet to be fully elucidated. One of the most widely accepted mediators known to play a …
have yet to be fully elucidated. One of the most widely accepted mediators known to play a …
GABAergic hypotheses of anxiety and depression: focus on GABA-B receptors.
Depression and anxiety are psychiatric disorders with high morbidity and comorbidity.
Because of multiple adverse effects of existing drugs and a low efficacy, therapy for a …
Because of multiple adverse effects of existing drugs and a low efficacy, therapy for a …
GABAergic contributions to the pathophysiology of depression and the mechanism of antidepressant action
G Sanacora, A Saricicek - CNS & Neurological Disorders-Drug …, 2007 - ingentaconnect.com
Increasing evidence suggests that abnormalities in amino neurotransmission are associated
with the neurobiology of depression. Preclinical studies demonstrate that GABA modulating …
with the neurobiology of depression. Preclinical studies demonstrate that GABA modulating …
The role of GABA in anxiety disorders
RB Lydiard - Journal of Clinical Psychiatry, 2003 - psychiatrist.com
Anxiety stems from and perpetuates dysregulation of neurobiological systems, but the exact
mechanisms of anxiety disorders are still only partially understood. Gamma-aminobutyric …
mechanisms of anxiety disorders are still only partially understood. Gamma-aminobutyric …
The GABA system in anxiety and depression and its therapeutic potential
H Möhler - Neuropharmacology, 2012 - Elsevier
In the regulation of behavior, the role of GABA neurons has been extensively studied in the
circuit of fear, where GABA interneurons play key parts in the acquisition, storage and …
circuit of fear, where GABA interneurons play key parts in the acquisition, storage and …