This review assesses the parallel data on the role of gamma‐aminobutyric acid (GABA) in
depression and anxiety. We review historical and new data from both animal and human …

This review assesses the parallel literature on the role of gamma‐aminobutyric acid (GABA)
in memory and anxiety. We review historical and new data from both animal and human …

Considerable evidence implicates the neurotransmitter γ-aminobutyric acid (GABA) in the
biochemical pathophysiology of mood disorders. Animal models of depression show …

Dysfunction of the gamma amino butyric acid (GABA)-ergic system has been purported to
play a role in psychiatric disorders, including anxiety and major depression. A clear link …

The authors review the available literature on the preclinical and clinical studies involving
GABAergic neurotransmission in mood disorders. γ-Aminobutyric acid (GABA) is an …

Mechanisms underlying the pathological characteristics of the various anxiety disorders
have yet to be fully elucidated. One of the most widely accepted mediators known to play a …

Depression and anxiety are psychiatric disorders with high morbidity and comorbidity.
Because of multiple adverse effects of existing drugs and a low efficacy, therapy for a …

Increasing evidence suggests that abnormalities in amino neurotransmission are associated
with the neurobiology of depression. Preclinical studies demonstrate that GABA modulating …

Anxiety stems from and perpetuates dysregulation of neurobiological systems, but the exact
mechanisms of anxiety disorders are still only partially understood. Gamma-aminobutyric …

In the regulation of behavior, the role of GABA neurons has been extensively studied in the
circuit of fear, where GABA interneurons play key parts in the acquisition, storage and …