Chronic pain can develop from numerous conditions and is one of the most widespread and
disabling health problems today. Unfortunately, the pathophysiology of chronic pain in most …

Emerging evidence suggests that chronic pain is a disease that can alter brain function.
Imaging studies have demonstrated structural remapping and functional reorganization of …

In this review, we present data from functional, structural, and molecular imaging studies in
patients and animals supporting the notion that it might be time to reconsider chronic pain as …

The somatosensory cortex remodels in response to sensory deprivation, with regions
deprived of input invaded by neighboring representations. The degree of cortical …

Since modern brain imaging of pain began 20 years ago, networks in the brain related to
pain processing and those related to different types of pain modulation, including placebo …

The great advances in brain imaging techniques over the last few decades have determined
a shift in our understanding of chronic pain conditions and opened the door for new …

Neuroimaging of pain and plasticity can provide a framework to understand the basic
mechanisms of pain regarding function, gray and white matter structure and connectivity …

The neuroimaging of experimental and clinical pain has revolutionised our understanding of
the physiological responses to pain and paved the way for a better understanding of the …

Recent neuroscientific evidence has confirmed the important role of cognitive and
behavioral factors in the development and treatment of chronic pain. Neuropathic and …

MR-based brain imaging technologies provide a suite of functional and structural metrics
that can be used to test hypotheses about the CNS mechanisms underlying pain perception …