In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum
LH Du Plessis, AC Van Niekerk, MM Maritz… - The Journal of …, 2012 - nature.com
The macrolide antibiotics, erythromycin and azithromycin, have been studied for their
potential antimalarial activity, but only modest activity has been demonstrated. In this study …
potential antimalarial activity, but only modest activity has been demonstrated. In this study …
Improved efficacy of doxycycline in liposomes against Plasmodium falciparum in culture and Plasmodium berghei infection in mice
V Rajendran, C Singh, PC Ghosh - Canadian Journal of …, 2018 - cdnsciencepub.com
The rate at which Plasmodium falciparum is developing resistance to clinically used
antimalarial drugs is alarming. Therefore, there is a compelling need to develop an efficient …
antimalarial drugs is alarming. Therefore, there is a compelling need to develop an efficient …
Selective lysis of erythrocytes infected with the trophozoite stage of Plasmodium falciparum by polyene macrolide antibiotics
UIM Wiehart, M Rautenbach, HC Hoppe - Biochemical pharmacology, 2006 - Elsevier
The continuous increase in strains of the human malaria parasite Plasmodium falciparum
resistant to most front-line antimalarial compounds is reason for grave clinical concern. The …
resistant to most front-line antimalarial compounds is reason for grave clinical concern. The …
Preparation of β-artemether liposomes, their HPLC–UV evaluation and relevance for clearing recrudescent parasitaemia in Plasmodium chabaudi malaria-infected …
B Chimanuka, M Gabriëls, MR Detaevernier… - … of Pharmaceutical and …, 2002 - Elsevier
Egg phosphatidylcholine-cholesterol liposome formulations containing the antimalarial drug
β-artemether have been prepared and analyzed for their encapsulating capacity, chemical …
β-artemether have been prepared and analyzed for their encapsulating capacity, chemical …
Formulation and evaluation of Pheroid vesicles containing mefloquine for the treatment of malaria
LH Du Plessis, C Helena… - Journal of Pharmacy …, 2014 - academic.oup.com
Objectives Mefloquine (MQ) is an antimalarial drug with high efficacy, often used in the
treatment and chemoprophylaxis of malaria. However, it has low solubility in water, a long …
treatment and chemoprophylaxis of malaria. However, it has low solubility in water, a long …
Assessment of the Induction of Dormant Ring Stages in Plasmodium falciparum Parasites by Artemisone and Artemisone Entrapped in Pheroid Vesicles In Vitro
L Grobler, M Chavchich, RK Haynes… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
The in vitro antimalarial activities of artemisone and artemisone entrapped in Pheroid
vesicles were compared, as was their ability to induce dormancy in Plasmodium falciparum …
vesicles were compared, as was their ability to induce dormancy in Plasmodium falciparum …
Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine‐Phosphatidylcholine Liposomes
We have examined the effect of stearylamine (SA) in liposomes on the viability of
Plasmodium falciparum in culture by studying the inhibition of incorporation of [3H] …
Plasmodium falciparum in culture by studying the inhibition of incorporation of [3H] …
Formulation development and evaluation of the anti-malaria properties of sustained release artesunate-loaded solid lipid microparticles based on phytolipids
Contexts: Artemisinins and its derivatives are considered the basis in the treatment of
Plasmodium falciparum malaria due to their high potency and rapid action. However, they …
Plasmodium falciparum malaria due to their high potency and rapid action. However, they …
Preparation, stability and in vitro evaluation of liposomes containing amodiaquine
JC Scholtz - 2010 - repository.nwu.ac.za
Malaria is a curable disease that claims nearly one million lives each year. Problems with
the treatment of malaria arise as resistance spreads and new treatment options are …
the treatment of malaria arise as resistance spreads and new treatment options are …
[HTML][HTML] Enhanced clearance of C. muridarum infection using azithromycin-loaded liposomes
Chlamydia trachomatis is an intracellular bacterium which infects around 129 million people
annually. Despite similar infection rates between sexes, most research investigating the …
annually. Despite similar infection rates between sexes, most research investigating the …
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