In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum

LH Du Plessis, AC Van Niekerk, MM Maritz… - The Journal of …, 2012 - nature.com
The macrolide antibiotics, erythromycin and azithromycin, have been studied for their
potential antimalarial activity, but only modest activity has been demonstrated. In this study …

Improved efficacy of doxycycline in liposomes against Plasmodium falciparum in culture and Plasmodium berghei infection in mice

V Rajendran, C Singh, PC Ghosh - Canadian Journal of …, 2018 - cdnsciencepub.com
The rate at which Plasmodium falciparum is developing resistance to clinically used
antimalarial drugs is alarming. Therefore, there is a compelling need to develop an efficient …

Selective lysis of erythrocytes infected with the trophozoite stage of Plasmodium falciparum by polyene macrolide antibiotics

UIM Wiehart, M Rautenbach, HC Hoppe - Biochemical pharmacology, 2006 - Elsevier
The continuous increase in strains of the human malaria parasite Plasmodium falciparum
resistant to most front-line antimalarial compounds is reason for grave clinical concern. The …

Preparation of β-artemether liposomes, their HPLC–UV evaluation and relevance for clearing recrudescent parasitaemia in Plasmodium chabaudi malaria-infected …

B Chimanuka, M Gabriëls, MR Detaevernier… - … of Pharmaceutical and …, 2002 - Elsevier
Egg phosphatidylcholine-cholesterol liposome formulations containing the antimalarial drug
β-artemether have been prepared and analyzed for their encapsulating capacity, chemical …

Formulation and evaluation of Pheroid vesicles containing mefloquine for the treatment of malaria

LH Du Plessis, C Helena… - Journal of Pharmacy …, 2014 - academic.oup.com
Objectives Mefloquine (MQ) is an antimalarial drug with high efficacy, often used in the
treatment and chemoprophylaxis of malaria. However, it has low solubility in water, a long …

Assessment of the Induction of Dormant Ring Stages in Plasmodium falciparum Parasites by Artemisone and Artemisone Entrapped in Pheroid Vesicles In Vitro

L Grobler, M Chavchich, RK Haynes… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
The in vitro antimalarial activities of artemisone and artemisone entrapped in Pheroid
vesicles were compared, as was their ability to induce dormancy in Plasmodium falciparum …

Inhibition of the Growth of Plasmodium falciparum in Culture by Stearylamine‐Phosphatidylcholine Liposomes

GM Hasan, N Garg, E Dogra, R Surolia… - Journal of …, 2011 - Wiley Online Library
We have examined the effect of stearylamine (SA) in liposomes on the viability of
Plasmodium falciparum in culture by studying the inhibition of incorporation of [3H] …

Formulation development and evaluation of the anti-malaria properties of sustained release artesunate-loaded solid lipid microparticles based on phytolipids

EE Chinaeke, SA Chime, VI Onyishi, AA Attama… - Drug …, 2015 - Taylor & Francis
Contexts: Artemisinins and its derivatives are considered the basis in the treatment of
Plasmodium falciparum malaria due to their high potency and rapid action. However, they …

Preparation, stability and in vitro evaluation of liposomes containing amodiaquine

JC Scholtz - 2010 - repository.nwu.ac.za
Malaria is a curable disease that claims nearly one million lives each year. Problems with
the treatment of malaria arise as resistance spreads and new treatment options are …

[HTML][HTML] Enhanced clearance of C. muridarum infection using azithromycin-loaded liposomes

Y Arasu, E Bryan, FA Russell, N Huettner… - International Journal of …, 2024 - Elsevier
Chlamydia trachomatis is an intracellular bacterium which infects around 129 million people
annually. Despite similar infection rates between sexes, most research investigating the …