[HTML][HTML] Hsa_circ_0136666 stimulates gastric cancer progression and tumor immune escape by regulating the miR-375/PRKDC Axis and PD-L1 phosphorylation

Z Miao, J Li, Y Wang, M Shi, X Gu, X Zhang, F Wei… - Molecular Cancer, 2023 - Springer
Background Targeted drugs are not quite effective for prolonging the survival of patients with
gastric cancer due to off-target effects as well as tumor immune escape mechanisms …

Hsa_circ_0001479 accelerates tumorigenesis of gastric cancer and mediates immune escape

J Zang, L Xiao, X Shi, S Liu, Y Wang, B Sun… - International …, 2023 - Elsevier
Gastric cancer (GC) is a common fatal malignant tumor of the digestive tract, particularly in
Asia. Circular RNA (circRNA) has been proved to regulate malignancy progression and …

[HTML][HTML] Hsa_circ_0044301 regulates gastric cancer cell's proliferation, migration, and invasion by modulating the Hsa-miR-188-5p/DAXX Axis and MAPK pathway

F Jiang, G Liu, X Chen, Q Li, F Fang, X Shen - Cancers, 2022 - mdpi.com
Simple Summary This study aimed to investigate whether circRNA could be potential
prognosis or therapeutic target. And we found the upregulated hsa_circ_0044301 was …

hsa_circ_0067514 suppresses gastric cancer progression and glycolysis via miR-654-3p/LATS2 axis.

SF Jiang, LI Rong-Rong - Neoplasma, 2022 - search.ebscohost.com
Gastric cancer is the third most frequent cancer with high prevalence and mortality globally.
Circular RNAs (circRNAs) play a key role in cancer regulation, including gastric cancer …

[HTML][HTML] Hsa_circ_0046523 mediates an immunosuppressive tumor microenvironment by regulating MiR-148a-3p/PD-L1 axis in pancreatic cancer

X Fu, G Sun, S Tu, K Fang, Y Xiong, Y Tu, M Zha… - Frontiers in …, 2022 - frontiersin.org
Background: Circular RNAs (circRNAs) are a novel type of non-coding RNA, play an
important role in the progression of tumors. However, the function and mechanism of …

[HTML][HTML] The circular RNA circDLG1 promotes gastric cancer progression and anti-PD-1 resistance through the regulation of CXCL12 by sponging miR-141-3p

DL Chen, H Sheng, DS Zhang, Y Jin, BT Zhao… - Molecular Cancer, 2021 - Springer
Abstract Background Dysregulation of circular RNAs (circRNAs) plays an important role in
the development of gastric cancer; thus, revealing the biological and molecular mechanisms …

Circular RNA hsa_circ_0026344 suppresses gastric cancer cell proliferation, migration and invasion via the miR-590-5p/PDCD4 axis

L Lv, J Du, D Wang, Z Yan - Journal of Pharmacy and …, 2022 - academic.oup.com
Abstract Objectives Circular RNA (CircRNA) is a class of non-coding RNA transcripts, with
multiple pathophysiological functions. Instead, the mechanism and function of circRNA in …

Circ_0067997 boosted the growth while repressed the apoptosis of SGC-7901/DDP cells via repressing miR-615-5p/AKT1 pathway

Y Jiao, Y Fu, Y Gong, G Wang, S Chen… - Cancer …, 2023 - content.iospress.com
BACKGROUND: Gastric cancer (GC) remains a huge challenge to the heathy of human
beings, largely due to lacking of effective therapeutic measures. Though an oncogenic role …

CircSCUBE3 Reduces the Anti-gastric Cancer Activity of Anti-PD-L1

HS Shan, XB Zhang, X Zhang, YT Wei, LL Meng… - Molecular …, 2024 - Springer
The progression of gastric cancer (GC) is closely related to tumor immune escape. The
research, therefore, studied the impact of possible circRNAs on the immune escape of GC …

[HTML][HTML] hsa_circ_0081143 promotes cisplatin resistance in gastric cancer by targeting miR-646/CDK6 pathway

M Xue, G Li, X Fang, L Wang, Y Jin, Q Zhou - Cancer cell international, 2019 - Springer
Background Increasing studies indicated that circRNAs play critical roles in tumor
progression. However, the roles and underlying mechanisms of circRNAs in gastric cancer …