Progestins as endocrine disrupters in aquatic ecosystems: concentrations, effects and risk assessment

K Fent - Environment international, 2015 - Elsevier
In aquatic ecosystems, progesterone (P4) and synthetic progestins (gestagens) originate
from excretion by humans and livestock. Synthetic progestins are used for contraception and …

Synthetic progestins in waste and surface waters: Concentrations, impacts and ecological risk

MJ Rocha, E Rocha - Toxics, 2022 - mdpi.com
Synthetic progestins (PGs) are a large family of hormones used in continuously growing
amounts in human and animal contraception and medicinal therapies. Because wastewater …

The challenge presented by progestins in ecotoxicological research: a critical review

V Kumar, AC Johnson, A Trubiroha… - … science & technology, 2015 - ACS Publications
Around 20 progestins (also called gestagens, progestogens, or progestagens) are used
today in assisting a range of medical conditions from endometrial cancer to uterine bleeding …

Effects of synthetic gestagens on fish reproduction

J Zeilinger, T Steger‐Hartmann, E Maser… - Environmental …, 2009 - Wiley Online Library
Although it is well known that estrogenic steroidal hormones are able to affect the sexual
development and reproduction of fish at low concentrations, no data on environmental …

[HTML][HTML] From single chemicals to mixtures—Reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow

TJ Runnalls, N Beresford, S Kugathas… - Aquatic Toxicology, 2015 - Elsevier
The aquatic environment is polluted with thousands of chemicals. It is currently unclear
which of these pose a significant threat to aquatic biota. The typical exposure scenario is …

Progestins and Antiprogestins Affect Gene Expression in Early Development in Zebrafish (Danio rerio) at Environmental Concentrations

S Zucchi, S Castiglioni, K Fent - Environmental science & …, 2012 - ACS Publications
Progesterone (P4) and synthetic progestins (gestagens) from contraceptives and hormone
therapy occur in treated wastewater and surface water, and they may have adverse effects …

Several synthetic progestins with different potencies adversely affect reproduction of fish

TJ Runnalls, N Beresford, E Losty… - … science & technology, 2013 - ACS Publications
Synthetic progestins are widely used as a component in both contraceptives and in hormone
replacement therapy (HRT), both on their own and in combination with EE2. Their presence …

Sources, concentrations, and exposure effects of environmental gestagens on fish and other aquatic wildlife, with an emphasis on reproduction

EF Orlando, LE Ellestad - General and comparative endocrinology, 2014 - Elsevier
Fish and other aquatic wildlife, including frogs, turtles, and alligators, have been used as
vertebrate sentinels for the effects of endocrine disrupting and other emerging chemicals of …

Comparing biological effects and potencies of estrone and 17β-estradiol in mature fathead minnows, Pimephales promelas

AA Dammann, NW Shappell, SE Bartell… - Aquatic Toxicology, 2011 - Elsevier
The presence of endocrine active compounds such as estrogens in treated wastewater
effluent and their effects on aquatic life are causing concern among aquatic resource …

Effects of progesterone on reproduction and embryonic development in the fathead minnow (Pimephales promelas)

ZA DeQuattro, EJ Peissig, DS Antkiewicz… - Environmental …, 2012 - Wiley Online Library
Abstract High concentrations (375 ng/L) of the steroid hormone progesterone (P4) were
measured in snowmelt runoff associated with large livestock‐feeding operations in …