[HTML][HTML] Structural diversity among Acinetobacter baumannii K-antigens and its implication in the in silico serotyping

J Roshini, LPP Patro, S Sundaresan… - Frontiers in …, 2023 - frontiersin.org
Acinetobacter baumannii is an emerging opportunistic pathogen. It exhibits multi-, extreme-,
and pan-drug resistance against several classes of antibiotics. Capsular polysaccharide …

[HTML][HTML] Bautype: capsule and Lipopolysaccharide serotype prediction for Acinetobacter baumannii genome

X Hua, Q Liang, L Fang, J He, M Wang… - Infectious Microbes & …, 2020 - journals.lww.com
Acinetobacter baumannii has three clusters of genes for polysaccharide synthesis. Capsular
polysaccharides and lipopolysaccharides are major virulence determinants in many Gram …

An update to the database for Acinetobacter baumannii capsular polysaccharide locus typing extends the extensive and diverse repertoire of genes found at and …

SM Cahill, RM Hall, JJ Kenyon - Microbial Genomics, 2022 - microbiologyresearch.org
Several novel non-antibiotic therapeutics for the critical priority bacterial pathogen,
Acinetobacter baumannii, rely on specificity to the cell-surface capsular polysaccharide …

EK3D: an E. coli K antigen 3-dimensional structure database

BR Kunduru, SA Nair, T Rathinavelan - Nucleic acids research, 2016 - academic.oup.com
A very high rate of multidrug resistance (MDR) seen among Gram-negative bacteria such as
Escherichia, Klebsiella, Salmonella, Shigella, etc. is a major threat to public health and …

[HTML][HTML] Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets

A Hassan, A Naz, A Obaid, RZ Paracha, K Naz… - BMC genomics, 2016 - Springer
Background Acinetobacter baumannii has emerged as a significant nosocomial pathogen
during the last few years, exhibiting resistance to almost all major classes of antibiotics …

[HTML][HTML] Delineating the Immuno-Dominant Antigenic Vaccine Peptides Against gacS-Sensor Kinase in Acinetobacter baumannii: An in silico Investigational …

AS Smiline Girija - Frontiers in Microbiology, 2020 - frontiersin.org
Objectives To predict the novel vaccine peptide candidates against gacS protein involved
with the citrate utilization in the two-component system of A. baumannii-associated virulence …

[HTML][HTML] Identification of antigens from nosocomial Acinetobacter baumannii clinical isolates in sera from ICU staff and infected patients using the antigenome …

T Nafarieh, M Bandehpour, A Hashemi… - World Journal of …, 2017 - Springer
Nosocomial infections with a bacterial origin are considered one of the most dangerous
threats to global health. Among the causes of these infections, Acinetobacter baumannii is …

Acinetobacter baumannii K27 and K44 capsular polysaccharides have the same K unit but different structures due to the presence of distinct wzy genes in otherwise …

AS Shashkov, JJ Kenyon, SN Senchenkova… - …, 2016 - academic.oup.com
Abstract Capsular polysaccharides (CPSs), from Acinetobacter baumannii isolates 1432,
4190 and NIPH 70, which have related gene content at the K locus, were examined, and the …

[HTML][HTML] International Clones of High Risk of Acinetobacter Baumannii—Definitions, History, Properties and Perspectives

A Shelenkov, V Akimkin, Y Mikhaylova - Microorganisms, 2023 - mdpi.com
Acinetobacter baumannii is a Gram-negative coccobacillus with exceptional survival skills in
an unfavorable environment and the ability to rapidly acquire antibiotic resistance, making it …

[HTML][HTML] Promising Acinetobacter baumannii Vaccine Candidates and Drug Targets in Recent Years

YC Tan, C Lahiri - Frontiers in Immunology, 2022 - frontiersin.org
In parallel to the uncontrolled use of antibiotics, the emergence of multidrug-resistant
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …