In addition to its recognized role in providing structural support, bone plays a crucial role in
maintaining the functionality and balance of various organs by secreting specific cytokines …

An imbalance in bone homeostasis results in bone loss and poor healing in bone diseases
and trauma. Osteoimmune interactions, as a key contributor to bone homeostasis, depend …

The skeletal system is an extraordinary structure that serves multiple purposes within the
body, including providing support, facilitating movement, and safeguarding vital organs …

Bones play crucial roles throughout life. Regardless of their size or shape, they offer
structural support for our bodies, shield internal organs and tissues, store vital minerals, and …

Throughout human life, bone is constantly in a delicate dynamic equilibrium of synthesis and
resorption, hosting finely-tuned bone mineral metabolic processes for bone homeostasis by …

Bone homeostasis is securely controlled by the dynamic well‐balanced actions among
osteoclasts, osteoblasts and osteocytes. Osteoclasts are large multinucleated cells that …

Osteoimmunology has gained momentum in recent years, focusing on the crosstalk between
the skeleton and the immune system. Extracellular vesicles (EVs) are nanoscale vesicles …

The mammalian skeleton is a metabolically active organ that continuously undergoes bone
remodeling, a process of tightly coupled bone resorption and formation throughout life …

Bone mass is controlled by the coordinated actions of osteoblasts and osteoclasts, cells
responsible for bone formation or bone resorption, respectively. It is now clear that the …

Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, play
an important role in cellular communication during skeletal growth and homeostasis …