We are using two modes of inflammation to trigger two different models of immune response:
innate and adaptive immune responses. Using continuous exposure to aerosolized …

Continuous exposure to aerosolized allergens leads to the activation of the innate and
adaptive immune system in the lung. Systemic inflammation in peripheral tissues has the …

Continuous exposure to aerosolized fine (particle size≤ 2.5 µm) and ultrafine (particle
size≤ 0.1 µm) particulates can trigger innate inflammatory responses in the lung and brain …

Background Asthma is a major public health problem worldwide. Emerging data from
epidemiological studies show that allergies and allergic diseases may be linked to anxiety …

Increasing evidence associates indoor fungal exposure with deleterious central nervous
system (CNS) health, such as cognitive and emotional deficits in children and adults, but the …

Background: Extended exposure to allergen exacerbates asthma symptoms, in part via
complex interactions between inflammatory cells and mediators. One consequence of these …

Background Chronic systemic inflammation affects brain functionality and may negatively
influence the progression of neurodegenerative disorders. Allergy is a chronic inflammatory …

Methods Segmental allergen bronchial provocation (SABP) was used to provoke airway
inflammation and retrieve airway cells to characterize cellular responses by RNA …

Bronchopulmonary inflammation, such as that associated with asthma, activates afferent
neural pathways. We recently demonstrated that localized inflammation in the lungs …

Background Asthma is a chronic inflammatory disease noteworthy for its vulnerability to
stress and emotion-induced symptom intensification. The fact that psychological stress and …