Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility
C Garlanda, B Bottazzi, A Bastone… - Annu. Rev …, 2005 - annualreviews.org
▪ Abstract C reactive protein, the first innate immunity receptor identified, and serum amyloid
P component are classic short pentraxins produced in the liver. Long pentraxins, including …
P component are classic short pentraxins produced in the liver. Long pentraxins, including …
The long pentraxin PTX3 as a link among innate immunity, inflammation, and female fertility
B Bottazzi, A Bastone, A Doni… - Journal of leukocyte …, 2006 - academic.oup.com
Abstract The long pentraxin 3 (PTX3) is member of a complex superfamily of multifunctional
proteins characterized by a cyclic multimeric structure. PTX3 is highly conserved in evolution …
proteins characterized by a cyclic multimeric structure. PTX3 is highly conserved in evolution …
Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation
L Deban, B Bottazzi, C Garlanda, YM de la Torre… - Biofactors, 2009 - Wiley Online Library
Pentraxins are a family of multimeric pattern recognition proteins highly conserved in
evolution. On the basis of the primary structure of the protomer, pentraxins are divided into …
evolution. On the basis of the primary structure of the protomer, pentraxins are divided into …
Pentraxins in innate immunity: from C-reactive protein to the long pentraxin PTX3
Pentraxins are a family of multimeric pattern-recognition proteins highly conserved in
evolution. Based on the primary structure of the subunit, the pentraxins are divided into two …
evolution. Based on the primary structure of the subunit, the pentraxins are divided into two …
Pentraxin 3, a non-redundant soluble pattern recognition receptor involved in innate immunity
Pentraxin 3 (PTX3) is the first long pentraxin identified. Long pentraxins consist of a C-
terminal pentraxin domain, which has sequence similarity to C-reactive protein (CRP) and …
terminal pentraxin domain, which has sequence similarity to C-reactive protein (CRP) and …
The long pentraxin PTX3 in vascular pathology
Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition
proteins characterized by a cyclic multimeric structure. Based on the primary structure of the …
proteins characterized by a cyclic multimeric structure. Based on the primary structure of the …
The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity
The innate immune system consists of a cellular arm and a humoral arm. Components of
humoral immunity include diverse molecular families, which represent functional ancestors …
humoral immunity include diverse molecular families, which represent functional ancestors …
Pathogen recognition by the long pentraxin PTX3
Innate immunity represents the first line of defence against pathogens and plays key roles in
activation and orientation of the adaptive immune response. The innate immune system …
activation and orientation of the adaptive immune response. The innate immune system …
The long pentraxin PTX3 at the crossroads between innate immunity and tissue remodelling
Innate immunity represents the first line of defence against pathogens and plays key roles in
the activation and orientation of the adaptive immune response. The innate immune system …
the activation and orientation of the adaptive immune response. The innate immune system …
Pentraxins in innate immunity: lessons from PTX3
The innate immune system constitutes the first line of defence against microorganisms and
plays a primordial role in the activation and regulation of adaptive immunity. The innate …
plays a primordial role in the activation and regulation of adaptive immunity. The innate …