[HTML][HTML] Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryos

B Tire, S Ozturk - Journal of Ovarian Research, 2023 - Springer
Telomeres are repetitive DNA sequences at eukaryotic chromosome ends and function in
maintaining genome integrity and stability. These unique structures undergo shortening due …

Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species

S Ozturk, B Sozen, N Demir - Molecular human reproduction, 2014 - academic.oup.com
Telomeres are located at the ends of all eukaryotic chromosomes and protect them from
deleterious events such as inappropriate DNA repair, illegitimate recombination or improper …

Telomeres, aging and reproduction

I Córdova-Oriz, L Chico-Sordo… - Current Opinion in …, 2022 - journals.lww.com
Recent evidence shows that telomeres are implicated in most processes related to female
fertility, embryo development and the newborn's health. Thus, telomere length and …

Telomere length: lights and shadows on their role in human reproduction

MS Rocca, C Foresta, A Ferlin - Biology of Reproduction, 2019 - academic.oup.com
Telomeres are repeated DNA sequences whose main function is to preserve genome
stability, protecting chromosomes ends from shortening caused by progressive loss during …

[HTML][HTML] Insights into the role of telomeres in human embryological parameters. Opinions regarding IVF

G Anifandis, M Samara, M Simopoulou… - Journal of …, 2021 - mdpi.com
Telomeres promote genome integrity by protecting chromosome ends from the activation of
the DNA damage response and protecting chromosomes from the loss of coding sequences …

Characterization of telomerase activity in the human oocyte and preimplantation embryo

DL Wright, EL Jones, JF Mayer… - Molecular human …, 2001 - academic.oup.com
Telomerase, a ribonucleoprotein, has been described as an essential component of highly
proliferative cells as it stabilizes the telomeres and avoids cellular senescence. The …

[HTML][HTML] Telomere DNA deficiency is associated with development of human embryonic aneuploidy

NR Treff, J Su, D Taylor, RT Scott Jr - PLoS genetics, 2011 - journals.plos.org
Aneuploidy represents the most prevalent form of genetic instability found in human
embryos and is the leading genetic cause of miscarriage and developmental delay in …

Telomere length and telomerase activity during folliculogenesis in mammals

EG Kosebent, F Uysal, S Ozturk - Journal of Reproduction and …, 2018 - jstage.jst.go.jp
Telomeres are repetitive non-coding DNA sequences located at the ends of chromosomes
in eukaryotic cells. Their most important function is to protect chromosome ends from being …

Telomere lengths in human oocytes, cleavage stage embryos and blastocysts

S Turner, HP Wong, J Rai… - Molecular human …, 2010 - academic.oup.com
Telomeres are repeated sequences that protect the ends of chromosomes and harbour DNA
repair proteins. Telomeres shorten during each cell division in the absence of telomerase …

Telomere length in human blastocysts

A Mania, A Mantzouratou, JDA Delhanty, G Baio… - Reproductive …, 2014 - Elsevier
This is a retrospective study aiming to assess telomere length in human embryos 4 days
post fertilization and to determine whether it is correlated to chromosomal ploidy, embryo …