[HTML][HTML] Induced sputum metabolomic profiles and oxidative stress are associated with chronic obstructive pulmonary disease (COPD) severity: potential use for …

T Zhu, S Li, J Wang, C Liu, L Gao, Y Zeng, R Mao… - EPMA Journal, 2020 - Springer
Chronic obstructive pulmonary disease (COPD) is a highly heterogeneous disease, and
metabolomics plays a hub role in predictive, preventive, and personalized medicine (PPPM) …

Plasma metabolomics and lipidomics reveal perturbed metabolites in different disease stages of chronic obstructive pulmonary disease

J Zhou, Q Li, C Liu, R Pang, Y Yin - International Journal of …, 2020 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) is a common disease
characterized by persistent respiratory symptoms and airflow restriction. It is usually …

[HTML][HTML] Metabolomics and transcriptomics pathway approach reveals outcome-specific perturbations in COPD

CI Cruickshank-Quinn, S Jacobson, G Hughes… - Scientific reports, 2018 - nature.com
Chronic obstructive pulmonary disease (COPD) comprises multiple phenotypes such as
airflow obstruction, emphysema, and frequent episodes of acute worsening of respiratory …

[HTML][HTML] An updated overview of metabolomic profile changes in chronic obstructive pulmonary disease

N Ran, Z Pang, Y Gu, H Pan, X Zuo, X Guan, Y Yuan… - Metabolites, 2019 - mdpi.com
Chronic obstructive pulmonary disease (COPD), a common and heterogeneous respiratory
disease, is characterized by persistent and incompletely reversible airflow limitation …

A novel metabolic score for predicting the acute exacerbation in patients with chronic obstructive pulmonary disease

L Peng, H You, M Xu, Z Dong, M Liu… - International Journal of …, 2023 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) has higher mortality when
developing to acute exacerbation (AECOPD); hence, the early intervention of COPD is …

Multi-omics study on biomarker and pathway discovery of chronic obstructive pulmonary disease

Y Tang, Z Chen, Z Fang, J Zhao, Y Zhou… - Journal of Breath …, 2021 - iopscience.iop.org
Chronic obstructive pulmonary disease (COPD) is a common heterogeneous respiratory
disease characterized by persistent and incompletely reversible airflow limitation. Due to the …

[HTML][HTML] Metabolome features of COPD: a scoping review

S Godbole, RP Bowler - Metabolites, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a complex heterogeneous disease state
with multiple phenotypic presentations that include chronic bronchitis and emphysema …

Identification of sputum biomarkers predictive of pulmonary exacerbations in COPD

CR Esther Jr, WK O'Neal, WH Anderson, M Kesimer… - Chest, 2022 - Elsevier
Background Improved understanding of the pathways associated with airway
pathophysiologic features in COPD will identify new predictive biomarkers and novel …

Integrating 3-omics data analyze rat lung tissue of COPD states and medical intervention by delineation of molecular and pathway alterations

J Li, P Zhao, L Yang, Y Li, Y Tian, S Li… - Bioscience reports, 2017 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) is a serious health problem. However, the
molecular pathogenesis of COPD remains unknown. Here, we explored the molecular …

[HTML][HTML] Bronchoalveolar lavage fluid from COPD patients reveals more compounds associated with disease than matched plasma

E Halper-Stromberg, L Gillenwater… - Metabolites, 2019 - mdpi.com
Smoking causes chronic obstructive pulmonary disease (COPD). Though recent studies
identified a COPD metabolomic signature in blood, no large studies examine the …