There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

In vivo imaging of molecular events in small animals has great potential to impact basic
science and drug development. For this reason, several imaging technologies have been …

In vivo fluorescence imaging uses a sensitive camera to detect fluorescence emission from
fluorophores in whole-body living small animals. To overcome the photon attenuation in …

The emerging clinical use of targeted fluorescent agents heralds a shift in intraoperative
imaging practices that overcome the limitations of human vision. However, in contrast to …

Fluorescence, the absorption and re-emission of photons with longer wavelengths, is one of
those amazing phenomena of Nature. Its discovery and utilization had, and still has, a major …

Recently, there has been tremendous interest in developing techniques such as MRI, micro-
CT, micro-PET, and SPECT to image function and processes in small animals. These …

In vivo fluorescence imaging with near‐infrared (NIR) light holds enormous potential for a
wide variety of molecular diagnostic and therapeutic applications. Because of its quantitative …

Fluorescent probes are one of the cornerstones of real-time imaging of live cells and a
powerful tool for cell biologists. They provide high sensitivity and great versatility while …

Fluorescence sampling of cellular function is widely used in all aspects of biology, allowing
the visualization of cellular and sub-cellular biological processes with spatial resolutions in …

Fluorescent tools have revolutionized our ability to probe biological dynamics, particularly at
the cellular level. Fluorescent sensors have been developed on several platforms, utilizing …