Biomaterial strategies for restorative therapies in Parkinson's disease
Parkinson's disease (PD) is a progressive neurological disorder, in which dopaminergic
midbrain neurons degenerate, leading to dopamine depletion that is associated with …
midbrain neurons degenerate, leading to dopamine depletion that is associated with …
Emerging regenerative medicine and tissue engineering strategies for Parkinson's disease
JP Harris, JC Burrell, LA Struzyna, HI Chen… - npj Parkinson's …, 2020 - nature.com
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disease, affecting 1–2% of people over 65. The classic motor symptoms of PD result from …
disease, affecting 1–2% of people over 65. The classic motor symptoms of PD result from …
Dopaminergic neurons transplanted using cell‐instructive biomaterials alleviate Parkinsonism in rodents
MM Adil, AT Rao, GN Ramadoss… - Advanced Functional …, 2018 - Wiley Online Library
Cell replacement therapy (CRT) is a promising treatment for degenerative disorders, such as
Parkinson's disease (PD). However, CRT is in general hindered by poor graft survival …
Parkinson's disease (PD). However, CRT is in general hindered by poor graft survival …
Progress in dopaminergic cell replacement and regenerative strategies for Parkinson's disease
W Chen, Q Huang, S Ma, M Li - ACS Chemical Neuroscience, 2018 - ACS Publications
Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder
symptomatically characterized by resting tremor, rigidity, bradykinesia, and gait impairment …
symptomatically characterized by resting tremor, rigidity, bradykinesia, and gait impairment …
Biomaterials in the treatment of Parkinson's disease
UM Krishnan - Neurochemistry International, 2021 - Elsevier
Parkinson's disease is a neurodegenerative disease, the treatment of which is mainly
centred around supplementation of dopamine. Additional targets have been identified and …
centred around supplementation of dopamine. Additional targets have been identified and …
Dopaminergic axon tracts within a hyaluronic acid hydrogel encasement for implantation to restore the nigrostriatal pathway
WJ Gordián-Vélez, KD Browne, JH Galarraga, JE Duda… - BioRxiv, 2021 - biorxiv.org
Parkinson's disease (PD) affects 10 million patients worldwide, making it the second most
prevalent neurodegenerative disease. Motor symptoms emerge from the loss of dopamine in …
prevalent neurodegenerative disease. Motor symptoms emerge from the loss of dopamine in …
Regenerative therapies for Parkinson's disease: An update
TB Stoker, RA Barker - BioDrugs, 2018 - Springer
Parkinson's disease is the second most common neurodegenerative disorder. It is
characterised by a typical movement disorder that occurs in part because of the selective …
characterised by a typical movement disorder that occurs in part because of the selective …
Primary tissue for cellular brain repair in Parkinson's disease: Promise, problems and the potential of biomaterials
The dopamine precursor, levodopa, remains the “gold standard” treatment for Parkinson's
disease, and, although it provides superlative efficacy in the early stages of the disease, its …
disease, and, although it provides superlative efficacy in the early stages of the disease, its …
Repairing the brain: cell replacement using stem cell-based technologies
C Henchcliffe, M Parmar - Journal of Parkinson's Disease, 2018 - content.iospress.com
Current approaches to cell replacement therapy in Parkinson's disease are strongly focused
on the dopamine system, with the view that restoring dopaminergic inputs in a localized and …
on the dopamine system, with the view that restoring dopaminergic inputs in a localized and …
Micro-and nanotechnology approaches to improve Parkinson's disease therapy
PV Torres-Ortega, L Saludas, AS Hanafy… - Journal of controlled …, 2019 - Elsevier
Current therapies for Parkinson's disease are symptomatic and unable to regenerate the
brain tissue. In recent years, the therapeutic potential of a wide variety of neuroprotective …
brain tissue. In recent years, the therapeutic potential of a wide variety of neuroprotective …