An evolutionary machine learning for pulmonary hypertension animal model from arterial blood gas analysis

B Shi, T Zhou, S Lv, M Wang, S Chen… - Computers in Biology …, 2022 - Elsevier
Pulmonary hypertension (PH) is a rare and fatal condition that leads to right heart failure and
death. The pathophysiology of PH and potential therapeutic approaches are yet unknown …

[HTML][HTML] Identification of pulmonary hypertension animal models using a new evolutionary machine learning framework based on blood routine indicators

J Hu, S Lv, T Zhou, H Chen, L Xiao, X Huang… - Journal of Bionic …, 2023 - Springer
Pulmonary Hypertension (PH) is a global health problem that affects about 1% of the global
population. Animal models of PH play a vital role in unraveling the pathophysiological …

Synergizing the enhanced RIME with fuzzy K-nearest neighbor for diagnose of pulmonary hypertension

X Yu, W Qin, X Lin, Z Shan, L Huang, Q Shao… - Computers in Biology …, 2023 - Elsevier
Pulmonary hypertension (PH) is an uncommon yet severe condition characterized by
sustained elevation of blood pressure in the pulmonary arteries. The delaying treatment can …

[HTML][HTML] Integrated bioinformatics analysis reveals marker genes and potential therapeutic targets for pulmonary arterial hypertension

A Li, J He, Z Zhang, S Jiang, Y Gao, Y Pan, H Wang… - Genes, 2021 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare cardiovascular disease with very high
mortality rate. The currently available therapeutic strategies, which improve symptoms …

[HTML][HTML] Integrated bioinformatics analysis reveals marker genes and immune infiltration for pulmonary arterial hypertension

S Tang, Y Liu, B Liu - Scientific reports, 2022 - nature.com
Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary syndrome with high
pulmonary vascular load and eventually causing RV heart failure even death. However, the …

[HTML][HTML] Integrated bioinformatic analysis reveals the underlying molecular mechanism of and potential drugs for pulmonary arterial hypertension

H Dong, X Li, M Cai, C Zhang, W Mao, Y Wang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disease without a
clear mechanism or drugs for treatment. Therefore, it is crucial to reveal the underlying …

Identification of differentially expressed genes associated with idiopathic pulmonary arterial hypertension by integrated bioinformatics approaches

E Zhao, H Xie, Y Zhang - Journal of Computational Biology, 2021 - liebertpub.com
Idiopathic pulmonary arterial hypertension (IPAH) is a fatal cardiovascular disease event
with significant morbidity and mortality. However, its potential molecular mechanisms and …

[HTML][HTML] Identification of potential biomarkers and immune infiltration characteristics in idiopathic pulmonary arterial hypertension using bioinformatics analysis

H Zeng, X Liu, Y Zhang - Frontiers in cardiovascular medicine, 2021 - frontiersin.org
Objectives: Idiopathic pulmonary arterial hypertension (IPAH) is a rare but severe lung
disorder, which may lead to heart failure and early mortality. However, little is known about …

An optimized machine learning method for predicting wogonin therapy for the treatment of pulmonary hypertension

Y Li, Y Fu, Y Liu, D Zhao, L Liu, S Bourouis… - Computers in Biology …, 2023 - Elsevier
Human health is at risk from pulmonary hypertension (PH), characterized by decreased
pulmonary vascular resistance and constriction of the pulmonary vessels, resulting in right …

Chaotic simulated annealing multi-verse optimization enhanced kernel extreme learning machine for medical diagnosis

J Liu, J Wei, AA Heidari, F Kuang, S Zhang… - Computers in Biology …, 2022 - Elsevier
Classification models such as Multi-Verse Optimization (MVO) play a vital role in disease
diagnosis. To improve the efficiency and accuracy of MVO, in this paper, the defects of MVO …