IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease

JO Jurado, V Pasquinelli, IB Alvarez… - Journal of leukocyte …, 2012 - academic.oup.com
Th1 lymphocytes are crucial in the immune response against Mycobacterium tuberculosis.
Nevertheless, IFN-γ alone is not sufficient in the complete eradication of the bacteria …

Reduced Th17 Response in Patients with Tuberculosis Correlates with IL-6R Expression on CD4+ T Cells

X Chen, M Zhang, M Liao, MW Graner… - American journal of …, 2010 - atsjournals.org
Rationale: Although it is well recognized that CD4+ T cells and T helper (Th) 1 cytokines are
critical in the cell-mediated response to Mycobacterium tuberculosis, it is also clear that this …

Comparison of interferon-γ-, interleukin (IL)-17-and IL-22-expressing CD4 T cells, IL-22-expressing granulocytes and proinflammatory cytokines during latent and …

J Cowan, S Pandey, LG Filion, JB Angel… - Clinical & …, 2012 - academic.oup.com
In this study, we investigated the role and expression of T helper type 17 (Th17) cells and
Th17 cytokines in human tuberculosis. We show that the basal proportion of interferon (IFN) …

IL-17 and Th17 cells in tuberculosis

E Torrado, AM Cooper - Cytokine & growth factor reviews, 2010 - Elsevier
Tuberculosis is primarily a disease of the lung. Constant expression of cellular immunity in
this organ is required to control Mycobacterium tuberculosis growth, but this can also result …

IL-23 and IL-17 in tuberculosis

SA Khader, AM Cooper - Cytokine, 2008 - Elsevier
Tuberculosis is a chronic disease requiring the constant expression of cellular immunity to
limit bacterial growth. The constant expression of immunity also results in chronic …

[HTML][HTML] Predominance of interleukin-22 over interleukin-17 at the site of disease in human tuberculosis

K Matthews, KA Wilkinson, B Kalsdorf, T Roberts… - Tuberculosis, 2011 - Elsevier
The inflammatory response to Mycobacterium tuberculosis (M. tb) at the site of disease is
Th1 driven. Whether the Th17 cytokines, IL-17 and IL-22, contribute to this response in …

Increased frequencies of T helper type 17 cells in tuberculous pleural effusion

T Wang, M Lv, Q Qian, Y Nie, L Yu, Y Hou - Tuberculosis, 2011 - Elsevier
Th17 cells have emerged as an important mediator in inflammatory and autoimmune
diseases. Recent studies suggest a potential impact of Th17 cells on tuberculosis (TB) …

Mycobacterium bovis BCG-Specific Th17 Cells Confer Partial Protection against Mycobacterium tuberculosis Infection in the Absence of Gamma Interferon

TM Wozniak, BM Saunders, AA Ryan… - Infection and …, 2010 - Am Soc Microbiol
Protective immunity against tuberculosis (TB) requires the integrated response of a network
of lymphocytes. Both gamma interferon (IFN-γ)-and interleukin 17 (IL-17)-secreting CD4+ T …

[PDF][PDF] IL-17 and IFN-γ production in peripheral blood following BCG vaccination and Mycobacterium tuberculosis infection in human.

Q Li, J Li, J Tian, B Zhu, Y Zhang… - European Review for …, 2012 - europeanreview.org
BACKGROUND: During Mycobacterium tuberculosis (Mtb) infection, cells of the im-mune
system rely on cytokines to regulate the activity of other immune and structural cells such as …

[HTML][HTML] Decreased IL-17 during treatment of sputum smear-positive pulmonary tuberculosis due to increased regulatory T cells and IL-10

L Xu, G Cui, H Jia, Y Zhu, Y Ding, J Chen, C Lu… - Journal of translational …, 2016 - Springer
Background Tuberculosis (TB) remains a major public health concern worldwide. Previous
studies have demonstrated that IL-17 plays an important role in initial immune response and …