Common protocols for the loading of 2-CTC and MBH-Br resins presume the application of
DCM, THF, or DMF; these solvents are considered as undesirable in accordance with …

The 2-chlorotrityl chloride (2-CTC) resin is one of the most frequently used and most
versatile resins for the large-scale manufacture of peptides. As a part of our efforts in …

Chlorotrityl Chloride (CTC) resin is one of the most useful resins for the solid‐phase
synthesis of C‐terminal acid peptides. CTC resin can be used for the preparation of both …

In solid-phase peptide synthesis, dichloromethane is the predominant solvent used to
incorporate the first amino acid on a 2-chlorotrityl chloride resin (via nucleophilic …

Here we evaluated the use of internal reference compounds for the rapid assessment of
reactions performed in solid-phase. An internal reference compound (commercially …

In recent years, the work of various research groups has allowed the substitution of the
hazardous solvents most widely used in solid-phase peptide synthesis, namely DMF, NMP …

In solid‐phase peptide synthesis, the nominal batch size is calculated using the starting
resin substitution and the mass of the starting resin. The starting resin substitution constitutes …

Abstract The N‐tetrachlorophthaloyl‐(TCP‐) amino protecting group has been evaluated for
use in solid‐phase peptide synthesis. The TCP group was unaffected by exposure to either …

Three types of resins, related to the spacer, environmental and microenvironmental models
were prepared by grafting commercial AMP polymer with 2-[2-(2-aminoethylamino)-2 …

Used in solid-phase peptide synthesis (SPPS) for peptides with an acid termination, the 2-
chlorotrityl chloride (2-CTC) resin is highly susceptible to moisture, leading to reduced resin …