The human transmembrane mucin MUC17 responds to TNFα by increased presentation at the plasma membrane
H Schneider, E Berger, B Dolan… - Biochemical …, 2019 - portlandpress.com
Transmembrane mucin MUC17 is an integral part of the glycocalyx as it covers the brush
border membrane of small intestinal enterocytes and presents an extended O-glycosylated …
border membrane of small intestinal enterocytes and presents an extended O-glycosylated …
The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small …
EK Malmberg, T Pelaseyed, ÅC Petersson… - Biochemical …, 2008 - portlandpress.com
The membrane-bound mucins have a heavily O-glycosylated extracellular domain, a single-
pass membrane domain and a short cytoplasmic tail. Three of the membrane-bound mucins …
pass membrane domain and a short cytoplasmic tail. Three of the membrane-bound mucins …
Muc17 protects intestinal epithelial cells from enteroinvasive E. coli infection by promoting epithelial barrier integrity
The membrane-bound mucin MUC17 (mouse homolog Muc3) is highly expressed on the
apical surface of intestinal epithelia and is thought to play a role in epithelial restitution and …
apical surface of intestinal epithelia and is thought to play a role in epithelial restitution and …
Human intestinal MUC17 mucin augments intestinal cell restitution and enhances healing of experimental colitis
The membrane-bound mucins, MUC17 (human) and Muc3 (mouse), are highly expressed
on the apical surface of intestinal epithelia and are thought to be cytoprotective. The …
on the apical surface of intestinal epithelia and are thought to be cytoprotective. The …
MUC13 negatively regulates tight junction proteins and intestinal epithelial barrier integrity via Protein Kinase C
C Segui-Perez, DAC Stapels, Z Ma, J Su… - Journal of Cell …, 2024 - journals.biologists.com
Glycosylated mucin proteins contribute to the essential barrier function of the intestinal
epithelium. The transmembrane mucin MUC13 is an abundant intestinal glycoprotein with …
epithelium. The transmembrane mucin MUC13 is an abundant intestinal glycoprotein with …
Stuck to MUC2
C Van Ooij - Nature Reviews Microbiology, 2010 - nature.com
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Evidence for a second peptide cleavage in the C-terminal domain of rodent intestinal mucin Muc3
IA Khatri, R Wang, JF Forstner - Biochemical Journal, 2004 - portlandpress.com
Rat intestinal mucin Muc3 (rMuc3), like its human homologue (MUC3) and several other
membrane mucins, contains a C-terminally located SEA (sea urchin sperm protein …
membrane mucins, contains a C-terminally located SEA (sea urchin sperm protein …
The role of the cell surface mucin MUC1 as a barrier to infection and regulator of inflammation
P Dhar, J McAuley - Frontiers in cellular and infection microbiology, 2019 - frontiersin.org
The family of cell surface (cs-) mucins are constitutively expressed at the cell surface by
nearly all epithelial cells, beneath the gel-mucin layer. All cs-mucin family members have …
nearly all epithelial cells, beneath the gel-mucin layer. All cs-mucin family members have …
Expression of intestinal MUC17 membrane-bound mucin in inflammatory and neoplastic diseases of the colon
Aim To determine the cellular location and expression of MUC17 mucin in specimens of
normal, inflamed and neoplastic colon. Methods Immunohistochemical analysis of human …
normal, inflamed and neoplastic colon. Methods Immunohistochemical analysis of human …
The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis
YH Sheng, R Lourie, SK Lindén, PL Jeffery, D Roche… - Gut, 2011 - gut.bmj.com
Background and Aims The MUC13 transmembrane mucin is highly and constitutively
expressed in the small and large intestine. Although MUC13 polymorphisms have been …
expressed in the small and large intestine. Although MUC13 polymorphisms have been …