Fate of systemically and locally administered adipose-derived mesenchymal stromal cells and their effect on wound healing

K Kallmeyer, D André-Lévigne, M Baquié… - Stem cells …, 2020 - academic.oup.com
There is increasing interest in the use of adipose-derived mesenchymal stromal cells (ASCs)
for wound repair. As the fate of administered cells is still poorly defined, we aimed to …

The effect of adipose‐derived stem cells on wound healing: Comparison of methods of application

H Kim, MR Hyun, SW Kim - Stem cells international, 2019 - Wiley Online Library
Impaired wound healing is a significant medical problem. Recently, cell‐based therapy
focused on stem cells has been developed to overcome the challenges of defective wound …

Adipose tissue-derived stromal cells for wound healing

P Goodarzi, S Alavi-Moghadam, M Sarvari… - Cell Biology and …, 2018 - Springer
Skin as the outer layer covers the body. Wounds can affect this vital organ negatively and
disrupt its functions. Wound healing as a biological process is initiated immediately after an …

Topically delivered adipose derived stem cells show an activated-fibroblast phenotype and enhance granulation tissue formation in skin wounds

SJ Hong, SX Jia, P Xie, W Xu, KP Leung, TA Mustoe… - PloS one, 2013 - journals.plos.org
Multipotent mesenchymal stem cells (MSCs) are found in various tissues and can proliferate
extensively in vitro. MSCs have been used in preclinical animal studies and clinical trials in …

Effects of adipose-derived stem cells and their conditioned medium in a human ex vivo wound model

X Guo, C Schaudinn, U Blume-Peytavi, A Vogt… - Cells, 2022 - mdpi.com
Adult stem cells have been extensively investigated for tissue repair therapies. Adipose-
derived stem cells (ASCs) were shown to improve wound healing by promoting re …

Augmentation of dermal wound healing by adipose tissue-derived stromal cells (ASC)

JA Van Dongen, MC Harmsen, B Van der Lei… - Bioengineering, 2018 - mdpi.com
The skin is the largest organ of the human body and is the first line of defense against
physical and biological damage. Thus, the skin is equipped to self-repair and regenerates …

Adipose‐derived stromal cells for nonhealing wounds: Emerging opportunities and challenges

M Deptuła, A Brzezicka, A Skoniecka… - Medicinal Research …, 2021 - Wiley Online Library
Wound healing complications affect thousands of people each year, thus constituting a
profound economic and medical burden. Chronic wounds are a highly complex problem that …

Adipose-derived mesenchymal stromal cells in regenerative medicine: state of play, current clinical trials, and future prospects

J Laloze, L Fiévet, A Desmoulière - Advances in Wound Care, 2021 - liebertpub.com
Significance: Wound healing is a complex process involving pain and inflammation, where
innervation plays a central role. Managing wound healing and pain remains an important …

Adipose‐derived stem cells for wound healing

A Hassanshahi, M Hassanshahi… - Journal of cellular …, 2019 - Wiley Online Library
Wound healing is a complex but a fine‐tuned biological process in which human skin has
the ability to regenerate itself following damage. However, in particular conditions such as …

Diabetes impairs adipose tissue–derived stem cell function and efficiency in promoting wound healing

F Cianfarani, G Toietta, G Di Rocco… - Wound repair and …, 2013 - Wiley Online Library
Adipose tissue–derived stem cells (ASC s) are gaining increasing consideration in tissue
repair therapeutic application. Recent evidence indicates that ASC s enhance skin repair in …