PURPOSE OF REVIEW This article is an update from the article on antiepileptic drug (AED)
therapy published in the last Continuum issue on epilepsy and is intended to cover the vast …

Abstract EDITOR'S NOTE The article “Update on Antiseizure Medications 2022” by Dr Abou-
Khalil was first published in the February 2016 Epilepsy issue of Continuum: Lifelong …

Despite the development of various new antiepileptic drugs (AEDs) since the early 1990s,
the available evidence indicates that the efficacy and tolerability of drug treatment of …

Nowadays a substantial armamentarium of antiepileptic drugs (AEDs) is available, including
drugs with different mechanisms of action, pharmacokinetics, efficacy and tolerability; …

Introduction: Epilepsy is one of the most common neurological diseases affecting
approximately 50 million people worldwide. Despite many advances in epilepsy research …

Significant advances have been made in the treatment of epilepsy over the past decades.
However, despite the development of various novel antiepileptic drugs, about one third of …

Clinical trials provide the evidence needed for rational use of medicines. The evolution of
drug trials follows largely the evolution of regulatory requirements. This article summarizes …

Effective new antiepileptic drugs (AEDs) are needed for the treatment of those with refractory
epilepsy. However, with the growing number of these drugs being licensed and marketed, a …

Summary The Twelfth Eilat Conference on New Antiepileptic Drugs (AEDs)–EILAT XII, took
place in Madrid, Spain from August 31st to September 3rd 2014. About 130 basic scientists …

Despite the current availability in the market of over two dozen antiepileptic drugs (AEDs),
about one third of people with epilepsy fail to achieve complete freedom from seizures with …