An official American Thoracic Society research statement: current challenges facing research and therapeutic advances in airway remodeling

YS Prakash, AJ Halayko, R Gosens… - American Journal of …, 2017 - atsjournals.org
Background: Airway remodeling (AR) is a prominent feature of asthma and other obstructive
lung diseases that is minimally affected by current treatments. The goals of this Official …

Airway remodeling in asthma

PG Woodruff, JV Fahy - Seminars in respiratory and critical care …, 2002 - thieme-connect.com
Airway remodeling is a summary term for the pathological changes that occur in airway
structure in allergic or suppurative airway diseases. Characteristic changes of airway …

[HTML][HTML] New targets for resolution of airway remodeling in obstructive lung diseases

AP Nayak, DA Deshpande, RB Penn - F1000Research, 2018 - ncbi.nlm.nih.gov
Airway remodeling (AR) is a progressive pathological feature of the obstructive lung
diseases, including asthma and chronic obstructive pulmonary disease (COPD). The …

Airway remodeling in asthma: update on mechanisms and therapeutic approaches

LP Boulet - Current opinion in pulmonary medicine, 2018 - journals.lww.com
Airway remodeling in asthma: update on mechanisms and therap... : Current Opinion in
Pulmonary Medicine Airway remodeling in asthma: update on mechanisms and therapeutic …

Airway remodeling from bench to bedside: current perspectives

DJ Slade, M Kraft - Clinics in chest medicine, 2006 - chestmed.theclinics.com
Our understanding of the mechanisms that lead to bronchospasm and airway inflammation
continues to evolve; however, it is clear that these phenomena vary among patients, and can …

[HTML][HTML] Airway remodeling in asthma: unanswered questions

JA Elias - American journal of respiratory and critical care …, 2000 - atsjournals.org
Asthma has traditionally been thought of as an entirely reversible disorder. As a
consequence, our therapeutic approach to this disorder has focused on symptomatic control …

Airway remodelling in asthma: current understanding and implications for future therapies

MLK Tang, JW Wilson, AG Stewart, SG Royce - Pharmacology & …, 2006 - Elsevier
Airway remodelling refers to the structural changes that occur in the airway wall in asthma.
These include epithelial hyperplasia and metaplasia, subepithelial fibrosis, muscle cell …

Understanding airway wall remodeling in asthma: a basis for improvements in therapy?

RK Kumar - Pharmacology & therapeutics, 2001 - Elsevier
Current strategies for the management of asthma focus on suppressing airway inflammation.
Other characteristic features of human asthma, such as airway hyperreactivity and the …

[HTML][HTML] Airway remodeling in asthma

KP Hough, ML Curtiss, TJ Blain, RM Liu, J Trevor… - Frontiers in …, 2020 - frontiersin.org
Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …

Airway remodeling: a potential therapeutic target in asthma

WX Zhang, CC Li - World Journal of Pediatrics, 2011 - Springer
Background Apart from airway inflammation, airway remodeling is one of the main
pathological features of asthma. However, it remains unclear when airway remodeling starts …