[HTML][HTML] Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the …

A Khan, Y Waheed, S Kuttikrishnan… - Frontiers in …, 2024 - frontiersin.org
In the current study, Neosetophomone B (NSP–B) was investigated for its anti-cancerous
potential using network pharmacology, quantum polarized ligand docking, molecular …

Network pharmacology, single gene survival analysis and molecular docking to study the mechanism of Sotetsuflavone in the treatment of pancreatic cancer

ZY Chu, XJ Zi - Pharmacological Research-Reports, 2024 - Elsevier
Pancreatic cancer is a highly lethal cancer with limited treatment options. The number of
pancreatic cancer patients is increasing rapidly worldwide. Many natural products have …

Network pharmacology integrated molecular docking reveals the antiosteosarcoma mechanism of biochanin A

Q Luo, X Shi, J Ding, Z Ma, X Chen… - Evidence‐Based …, 2019 - Wiley Online Library
Background. As the malignant tumor with the highest incidence in teenagers, osteosarcoma
has become a major problem in oncology research. In addition to surgical management, the …

[HTML][HTML] Fibroblast growth factor 2 is a druggable target against glioblastoma: A computational investigation

R Siddique, SA Abideen, G Nabi, FM Awan… - Frontiers in …, 2022 - frontiersin.org
Fibroblast growth factor 2 (FGF2) is a key player in cancer and tissue homeostasis and
regulates renewal of several stem cell types. The FGF2 role in malignant glioma is proven …

[Retracted] Network Pharmacology Prediction: The Possible Mechanisms of Cinobufotalin against Osteosarcoma

R Chen, Z Guan, X Zhong, W Zhang… - … Methods in Medicine, 2022 - Wiley Online Library
Objective. To explore the active compounds and targets of cinobufotalin (huachansu)
compared with the osteosarcoma genes to obtain the potential therapeutic targets and …

[HTML][HTML] Mechanisms underlying the therapeutic effects of cinobufagin in treating melanoma based on network pharmacology, single-cell RNA sequencing data …

J Yang, C Cheng, Z Wu - Frontiers in Pharmacology, 2024 - frontiersin.org
Malignant melanoma is one of the most aggressive of cancers; if not treated early, it can
metastasize rapidly. Therefore, drug therapy plays an important role in the treatment of …

Integrating network pharmacology approaches for the investigation of multi-target pharmacological mechanism of 6-shogaol against cervical cancer

AM Elasbali, WA Al-Soud… - Journal of …, 2023 - Taylor & Francis
Traditional treatment of cancer has been plagued by a number of obstacles, such as multiple
drug resistance, toxicity and financial constraints. In contrast, phytochemicals that modulate …

[HTML][HTML] Targeting potential receptor molecules in non-small cell lung cancer (NSCLC) using in silico approaches

C Kirubhanand, J Merciline Leonora… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: Non-Small Cell Lung Cancer is the most prevalent type of cancer in lung
cancer. Chemotherapy, radiation therapy, and other conventional cancer treatments have a …

[HTML][HTML] A Comprehensive in silico exploration of pharmacological properties, bioactivities, molecular docking, and anticancer potential of vieloplain F from Xylopia …

SS Hassan, SQ Abbas, F Ali, M Ishaq, I Bano… - Molecules, 2022 - mdpi.com
Compounds derived from plants have several anticancer properties. In the current study,
one guaiane-type sesquiterpene dimer, vieloplain F, isolated from Xylopia vielana species …

Network pharmacology and molecular docking study-based approach to explore mechanism of benzimidazole-based anthelmintics for the treatment of lung cancer

A Garg, S Karhana, A Bano, IA Khan… - Journal of …, 2023 - Taylor & Francis
Emerging studies have reported the potential anticancer activity of benzimidazole-based
anthelmintics (BBA) against lung cancer (LC). However, mechanism underlying the …