Cytokines such as interleukins, chemokines and interferons are immunomodulating and
inflammatory agents, characterized by considerable redundancy, in that many cytokines …

The IL-1 family of cytokines encompasses eleven proteins that each share a similar-barrel
structure and bind to Ig-like receptors. Some of the IL-1-like cytokines have been well …

Abstract Interleukin 37 (IL-37) is a new member of the IL-1 family which all have a similar β-
barrel structure. Since its discovery, IL-37 has been studied extensively in immunological …

This article provides an overview of the biological function of a recently discovered cytokine,
IL-37, formerly referred to as IL-1F7, and its role in chronic inflammation and autoimmune …

Trained immunity (TI) is a de facto innate immune memory program induced in monocytes/
macrophages by exposure to pathogens or vaccines, which evolved as protection against …

Interleukin-1 family 7 (IL-1F7) is a novel member of IL-1F cytokines. IL-1F7 is more
commonly known as IL-37. IL-37 join the α-subunit of the IL-18 receptor, or IL-18 binding …

Abstract Interleukin-37 (IL-37) is a newly introduced cytokine to interleukin-1 family. Many
studies have demonstrated that IL-37 owns immunosuppressive effects against both innate …

Abstract Interleukin (IL)-37, a new IL-1 family member, has received increasing attention in
recent years. In the past decade, it has been determined that IL‑37 is expressed in various …

An estimated 5–8% of the world's population is afflicted by severe inflammatory diseases
that are among the leading causes of death, particularly in women younger than 65 years in …

The recently identified cytokines—interleukin (IL)-35 and interleukin (IL)-37—have been
described for their anti-inflammatory and immune-modulating actions in numerous …