Estetrol/drospirenone: a review in oral contraception
A Lee, YY Syed - Drugs, 2022 - Springer
Estetrol/drospirenone is a combined oral contraceptive (COC) with a plant-synthesised
foetal oestrogen (estetrol) and a well-established progestin (drospirenone). In preclinical …
foetal oestrogen (estetrol) and a well-established progestin (drospirenone). In preclinical …
[HTML][HTML] Estetrol-drospirenone combination oral contraceptive: North American phase 3 efficacy and safety results
MD Creinin, CL Westhoff, C Bouchard, MJ Chen… - Contraception, 2021 - Elsevier
Objective To assess efficacy, cycle control, and safety of an oral contraceptive containing
estetrol (E4) 15 mg and drospirenone (DRSP) 3 mg. Study design Women aged 16 to 50 …
estetrol (E4) 15 mg and drospirenone (DRSP) 3 mg. Study design Women aged 16 to 50 …
[HTML][HTML] Tolerability and safety of the estetrol/drospirenone combined oral contraceptive: Pooled analysis of two multicenter, open-label phase 3 trials
Objectives: To evaluate tolerability and safety of estetrol (E4) 15 mg/drospirenone (DRSP) 3
mg oral contraceptive using pooled data from two, multicenter, phase 3 trials. Study design …
mg oral contraceptive using pooled data from two, multicenter, phase 3 trials. Study design …
[HTML][HTML] Pooled efficacy results of estetrol/drospirenone combined oral contraception phase 3 trials
Objective To evaluate overall and subgroup efficacy of an estetrol (E4) 15 mg drospirenone
(DRSP) 3 mg oral contraceptive in a 24/4-day regimen. Study design We pooled efficacy …
(DRSP) 3 mg oral contraceptive in a 24/4-day regimen. Study design We pooled efficacy …
Estetrol‐Drospirenone combination oral contraceptive: a clinical study of contraceptive efficacy, bleeding pattern and safety in Europe and Russia
K Gemzell‐Danielsson, D Apter, J Zatik… - … Journal of Obstetrics …, 2022 - Wiley Online Library
Objectives To assess the contraceptive efficacy, bleeding pattern and safety of a combined
oral contraceptive containing estetrol (E4) 15 mg and drospirenone (DRSP) 3 mg. Design …
oral contraceptive containing estetrol (E4) 15 mg and drospirenone (DRSP) 3 mg. Design …
A novel estetrol-containing combined oral contraceptive: European expert panel review
K Gemzell-Danielsson, A Cagnacci… - … European Journal of …, 2022 - Taylor & Francis
Purpose Despite considerable advances in recently developed combined oral
contraceptives (COCs), resulting in lower rates of adverse events while maintaining …
contraceptives (COCs), resulting in lower rates of adverse events while maintaining …
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause
C Gérard, JF Arnal, M Jost, J Douxfils… - Expert review of …, 2022 - Taylor & Francis
Introduction Estrogens used in women's healthcare have been associated with increased
risks of venous thromboembolism (VTE) and breast cancer. Estetrol (E4), an estrogen …
risks of venous thromboembolism (VTE) and breast cancer. Estetrol (E4), an estrogen …
[HTML][HTML] Endocrine and metabolic effects of an oral contraceptive containing estetrol and drospirenone
C Klipping, I Duijkers, M Mawet, C Maillard, A Bastidas… - Contraception, 2021 - Elsevier
Objectives To evaluate the effect on endocrine and metabolic parameters of a new
combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP) …
combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP) …
Estetrol: a new choice for contraception
F Fruzzetti, T Fidecicchi, MM Montt Guevara… - Journal of Clinical …, 2021 - mdpi.com
Estetrol (E4) is a natural estrogenic steroid that is normally produced by human fetal liver.
Recent research has demonstrated that it is a potent, orally bioavailable, natural selective …
Recent research has demonstrated that it is a potent, orally bioavailable, natural selective …
Reduced hemostatic effects with drospirenone-based oral contraceptives containing estetrol vs. ethinyl estradiol
C Kluft, Y Zimmerman, M Mawet, C Klipping… - Contraception, 2017 - Elsevier
Objective The effects of estetrol (E4), a natural fetal estrogen, combined with drospirenone
(DRSP) were evaluated on plasma levels of sex hormone-binding globulin (SHBG) …
(DRSP) were evaluated on plasma levels of sex hormone-binding globulin (SHBG) …
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