[HTML][HTML] Baseline prognostic nutritional index and changes in pretreatment body mass index associate with immunotherapy response in patients with advanced cancer

P Johannet, A Sawyers, Y Qian, S Kozloff… - … for ImmunoTherapy of …, 2020 - ncbi.nlm.nih.gov
Background Recent research suggests that baseline body mass index (BMI) is associated
with response to immunotherapy. In this study, we test the hypothesis that worsening …

Nutritional status as a predictive biomarker for immunotherapy outcomes in advanced head and neck cancer

M Guller, M Herberg, N Amin, H Alkhatib, C Maroun… - Cancers, 2021 - mdpi.com
Simple Summary Tumors of head and neck cancer are a heterogenous collection of
malignancies affecting the upper aerodigestive tract, the majority of which are head and …

Protective effect of obesity on survival in cancers treated with immunotherapy vanishes when controlling for type of cancer, weight loss and reduced skeletal muscle

S Antoun, E Lanoy, S Ammari, S Farhane… - European Journal of …, 2023 - Elsevier
Introduction Association of high body mass index (BMI) with longer survival has been
reported in patients on immune checkpoint inhibitors (ICIs), but results are inconsistent. This …

Pretreatment body mass index and clinical outcomes in cancer patients following immune checkpoint inhibitors: a systematic review and meta-analysis

H Chen, D Wang, Q Zhong, Y Tao, Y Zhou… - Cancer Immunology …, 2020 - Springer
Background This systematic review and meta-analysis aimed to evaluate the association
between pretreatment body mass index (BMI) and clinical outcomes in cancer patients …

[HTML][HTML] Prognostic effect of body mass index in patients with advanced NSCLC treated with chemoimmunotherapy combinations

A Cortellini, B Ricciuti, VR Vaz, D Soldato… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Methods In this international multicenter study, we evaluated the association between
baseline BMI, progression-free survival (PFS) and overall survival (OS) in a cohort of …

The complex relationship between body mass index and response to immune checkpoint inhibition in metastatic melanoma patients

D Donnelly, S Bajaj, J Yu, M Hsu, A Balar… - … for immunotherapy of …, 2019 - Springer
Despite major improvements in combatting metastatic melanoma since the advent of
immunotherapy, the overall survival for patients with advanced disease remains low …

Adiposity may predict survival in patients with advanced stage cancer treated with immunotherapy in phase 1 clinical trials

DJ Martini, MR Kline, Y Liu, JM Shabto, MA Williams… - Cancer, 2020 - Wiley Online Library
Background Body mass index (BMI) is used to define obesity, but it is an imperfect measure
of body composition. In the current study, the authors explored the association between …

[HTML][HTML] The prognostic role of obesity is independent of sex in cancer patients treated with immune checkpoint inhibitors: A pooled analysis of 4090 cancer patients

H Xu, D Cao, A He, W Ge - International Immunopharmacology, 2019 - Elsevier
Objective Recent studies suggest obesity is associated with improved survival of cancer
patients treated with immune checkpoint inhibitors (ICIs). We performed this meta-analysis to …

Prognostic nutritional index predicts response and prognosis in cancer patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis

L Ni, J Huang, J Ding, J Kou, T Shao, J Li, L Gao… - Frontiers in …, 2022 - frontiersin.org
Objective To investigate the association between pretreatment prognostic nutritional index
(PNI) and clinical survival outcomes for advanced-stage cancer patients treated with …

Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint …

GS Naik, SS Waikar, AEW Johnson… - … for immunotherapy of …, 2019 - Springer
Background A male gender driven obesity paradox (improved survival for overweight/obese
patients compared to normal weight) was recently shown in melanoma in the context of …