La kinase Aurora A est une protéine essentielle au cycle cellulaire et plus particulièrement
lors de la mitose. En effet, Aurora A est nécessaire à l'entrée en mitose et joue un rôle dans …

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Aurora kinase A and B share great similarity in sequences, structures, and phosphorylation
motif, yet they show different localizations and play distinct crucial roles. The factors that …

Aurora kinases are master regulators of mitosis. Aurora kinase A is necessary for
centrosome separation and maturation and for the assembly of a functional bipolar spindle …

Background: Aurora kinases show different localizations and play distinct roles, yet the
mechanisms remain largely unknown. Results: Different localization leads to functional …

Aurora A is a serine/threonine kinase that is essential for a wide variety of cell‐cycle‐related
events, but only a small number of its substrates are known. We present and validate a …

Aurora family of protein kinases have emerged as crucial factors of, not only mitosis and
cytokinesis, but also human carcinogenesis. Among these family members is Aurora-A that …

Temporally and spatially controlled activation of the Aurora A kinase (AURKA) regulates
centrosome maturation, entry into mitosis, formation and function of the bipolar spindle, and …

Aurora-A is a serine/threonine kinase that has oncogenic properties in vivo. The expression
and kinase activity of Aurora-A are up-regulated in many cancers including prostate cancer …

The Aurora-A kinase regulates cell division, by controlling centrosome biology and spindle
assembly. Cancer cells often display elevated levels of the kinase, due to amplification of the …