Growth hormone (GH) research and its clinical application for the treatment of growth
disorders span more than a century. During the first half of the 20th century, clinical …

The growth hormone (GH) cascade and the remarkable advances over the past four
decades in our knowledge of its components are considered. It is now over 40 years since …

Growth hormone (GH) therapy has been appropriate for severely GH-deficient children and
adolescents since the 1960s. Use for other conditions for which short stature was a …

Although the importance of the pituitary gland for growth was recognized in late 19 th
century, Growth hormone (GH) therapy was made available for severely GH-deficient …

Context: Treatment of GH-deficient adolescents in transition to adulthood remains
challenging. Objective: The objective was to assess the safety and efficacy of GH in GH …

The availability of synthetic recombinant human growth hormone (GH) in potentially
unlimited quantities since the 1980s has improved understanding of the many nonstatural …

A number of tissues, including the brain, pituitary, immune system, placenta, mammary
gland, and testis, may be self-contained units of GH regulation, production, and action. The …

Growth hormone (GH) is a major regulatory factor for overall body growth as evidenced by
the height extremes in people with abnormal circulating GH levels or GH receptor (GHR) …

The syndrome of impaired GH secretion (GH deficiency) in childhood and adolescence had
been identified at the end of the 19 th century. Its non-acquired variant (naGHD) is, at …

Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical
practice more than 20 years ago. Since then, a great volume of experience has been …