Abstract Objective: FAT3 and LRP1B are two tumor suppressor genes with high mutation
frequency in multiple cancer types, we sought to investigate the prognostic and …

Background Uterine corpus endometrial carcinoma (UCEC) ranks sixth among malignant
tumors in women and the mortality is still rising. FAT2 gene has been considered to be …

Objective Tumor immune microenvironmental features may predict survival and guide
treatment. This study aimed to comprehensively decipher the immunological features of …

Immunotherapy is a practical and promising treatment for advanced and recurrent
endometrial cancer (EC). In this study, we identified an immune-related gene (IRG) …

To explore the prognostic value of tumor mutation burden (TMB) and its correlation with
immune infiltrates in endometrial cancer. Transcriptome and somatic mutation profiles of …

Purpose: Tumors with high mutation load are thought to engender stronger immune
responses, which in turn promote prolonged patient survival. To investigate this, we …

Endometrial cancer (EC), one of the most common gynecological malignancies, has been
gradually increasing worldwide. The Cancer Genome Atlas endometrial collaborative …

Background POLE is a critical biomarker for endometrial cancer (ECs) prognosis and
therapeutic decision. However, the immune infiltration and immunotherapy-related gene …

Current molecular classification approaches for endometrial cancer (EC) often employ
multiple testing platforms. Some subtypes still lack univocal prognostic significance …

Objective Although Polymerase-epsilon (POLE)-mutated and mismatch repair (MMR)-
deficient endometrial cancers (ECs) are considered as promising candidates for anti-PD …