Connexin and pannexin signaling in gastrointestinal and liver disease

M Maes, SC Yanguas, J Willebrords, B Cogliati… - Translational …, 2015 - Elsevier
Gap junctions, which mediate intercellular communication, are key players in digestive
homeostasis. They are also frequently involved in gastrointestinal and liver pathology. This …

Roles of connexins and pannexins in digestive homeostasis

M Maes, B Cogliati, S Crespo Yanguas… - Cellular and molecular …, 2015 - Springer
Connexin proteins are abundantly present in the digestive system. They primarily form gap
junctions, which control the intercellular exchange of critical homeostasis regulators. By …

[PDF][PDF] Connexin and pannexin (hemi) channels: Emerging targets in the treatment of liver disease

A Cooreman, R Van Campenhout, S Ballet… - …, 2019 - Wiley Online Library
Connexin proteins are the building blocks of hemichannels, which dock further between
adjacent cells to form gap junctions. Gap junctions control the intercellular exchange of …

Connexin and pannexin (hemi) channels in the liver

M Maes, E Decrock, B Cogliati, AG Oliveira… - Frontiers in …, 2014 - frontiersin.org
The liver was among the first organs in which connexin proteins have been identified.
Hepatocytes harbor connexin32 and connexin26, while non-parenchymal liver cells typically …

Introduction: connexins, pannexins and their channels as gatekeepers of organ physiology

M Vinken - Cellular and Molecular Life Sciences, 2015 - Springer
Homeostasis relies on the intimate interplay between extracellular, intracellular and
intercellular signaling networks. Direct communication between adjacent cells is mediated …

[HTML][HTML] Connexins and pannexins in liver damage

SC Yanguas, J Willebrords, M Maes, TC da Silva… - EXCLI …, 2016 - ncbi.nlm.nih.gov
Connexins and pannexins are key players in the control of cellular communication and thus
in the maintenance of tissue homeostasis. Inherent to this function these proteins are …

Regulation of connexin‐and pannexin‐based channels by post‐translational modifications

C D'hondt, J Iyyathurai, M Vinken, V Rogiers… - Biology of the …, 2013 - Wiley Online Library
Connexin (Cx) and pannexin (Panx) proteins form large conductance channels, which
function as regulators of communication between neighbouring cells via gap junctions …

Connexins and pannexins in vascular function and disease

F Molica, XF Figueroa, BR Kwak, BE Isakson… - International journal of …, 2018 - mdpi.com
Connexins (Cxs) and pannexins (Panxs) are ubiquitous membrane channel forming
proteins that are critically involved in many aspects of vascular physiology and pathology …

Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles

C Giaume, L Leybaert, C C. Naus… - Frontiers in …, 2013 - frontiersin.org
Functional interaction between neurons and glia is an exciting field that has expanded
tremendously during the past decade. Such partnership has multiple impacts on neuronal …

Connexin and pannexin signaling pathways, an architectural blueprint for CNS physiology and pathology?

E Decrock, M De Bock, N Wang, G Bultynck… - Cellular and molecular …, 2015 - Springer
The central nervous system (CNS) is composed of a highly heterogeneous population of
cells. Dynamic interactions between different compartments (neuronal, glial, and vascular …