[HTML][HTML] Parallels in immunometabolic adipose tissue dysfunction with ageing and obesity

W Trim, JE Turner, D Thompson - Frontiers in immunology, 2018 - frontiersin.org
Ageing, like obesity, is often associated with alterations in metabolic and inflammatory
processes resulting in morbidity from diseases characterised by poor metabolic control …

[HTML][HTML] The immune landscape of visceral adipose tissue during obesity and aging

S Khan, YT Chan, XS Revelo, DA Winer - Frontiers in endocrinology, 2020 - frontiersin.org
Obesity and aging represent major health burdens to the global adult population. Both
conditions promote the development of associated metabolic diseases such as insulin …

[HTML][HTML] White adipose tissue dysfunction in obesity and aging

M Reyes-Farias, J Fos-Domenech, D Serra… - Biochemical …, 2021 - Elsevier
Both obesity and aging are associated with the development of metabolic diseases such as
type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose …

Changes in adipose tissue macrophages and T cells during aging

SK Garg, C Delaney, H Shi… - Critical Reviews™ in …, 2014 - dl.begellhouse.com
Adipose tissue historically was believed to be an inert tissue, functioning primarily in the
storage of energy and thermal homeostasis. However, recent discoveries point toward a …

Adipose tissue, immune aging, and cellular senescence

D Frasca, BB Blomberg - Seminars in immunopathology, 2020 - Springer
Obesity represents a serious health problem as it is rapidly increasing worldwide. Obesity is
associated with reduced healthspan and lifespan, decreased responses to infections and …

Innate immune control of adipose tissue homeostasis

H Kane, L Lynch - Trends in immunology, 2019 - cell.com
Adipose tissue is a critical regulator of systemic metabolism and normal bodily homeostasis.
Recently, the immune system has been implicated in the regulation of adipose tissue …

Chronic adipose tissue inflammation: all immune cells on the stage

G Cildir, SC Akıncılar, V Tergaonkar - Trends in molecular medicine, 2013 - cell.com
Inflammation is indispensable for host homeostasis against invading pathogens and efficient
wound healing upon tissue malfunction and has to be tightly controlled by various …

[HTML][HTML] Interplay between the immune system and adipose tissue in obesity

MA Exley, L Hand, D O'Shea… - Journal of …, 2014 - joe.bioscientifica.com
Obesity is a major risk factor for metabolic disease, with white adipose tissue (WAT)
inflammation emerging as a key underlying pathology. Alongside its major role in energy …

[HTML][HTML] Aging, obesity, and inflammatory age-related diseases

D Frasca, BB Blomberg, R Paganelli - Frontiers in immunology, 2017 - frontiersin.org
The increase in the prevalence of obesity represents a worldwide phenomenon in all age
groups and is pathologically and genetically correlated with several metabolic and …

Adipose tissue inflammation: novel insight into the role of macrophages and lymphocytes

H Sell, J Eckel - Current Opinion in Clinical Nutrition & Metabolic …, 2010 - journals.lww.com
This review summarizes strong evidence for a link between the action of innate and adaptive
immune systems in adipose tissue in the context of obesity and metabolism in rodents, but …