Standards and methodological rigor in pulmonary arterial hypertension preclinical and translational research
S Provencher, SL Archer, FD Ramirez… - Circulation …, 2018 - Am Heart Assoc
Despite advances in our understanding of the pathophysiology and the management of
pulmonary arterial hypertension (PAH), significant therapeutic gaps remain for this …
pulmonary arterial hypertension (PAH), significant therapeutic gaps remain for this …
Translating research into improved patient care in pulmonary arterial hypertension
S Bonnet, S Provencher, C Guignabert… - American journal of …, 2017 - atsjournals.org
We have witnessed significant advances in the management of pulmonary arterial
hypertension (PAH)(1), a rare and severe condition characterized by intense pulmonary …
hypertension (PAH)(1), a rare and severe condition characterized by intense pulmonary …
Pulmonary arterial hypertension: challenges in translational research and a vision for change
G Sutendra, ED Michelakis - Science translational medicine, 2013 - science.org
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with a relentless
course toward heart failure and early death. Existing PAH therapies, all of which were …
course toward heart failure and early death. Existing PAH therapies, all of which were …
Clinical trial design and new therapies for pulmonary arterial hypertension
O Sitbon, M Gomberg-Maitland… - European …, 2019 - Eur Respiratory Soc
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on
case reports and small series, and was largely ineffectual. As a deeper understanding of the …
case reports and small series, and was largely ineffectual. As a deeper understanding of the …
Pulmonary arterial hypertension: pathophysiology and treatment
NSH Lan, BD Massam, SS Kulkarni, CC Lang - Diseases, 2018 - mdpi.com
Pulmonary arterial hypertension (PAH), the first category of pulmonary hypertension, is a
chronic and progressive disorder characterised by angioproliferative vasculopathy in the …
chronic and progressive disorder characterised by angioproliferative vasculopathy in the …
Emerging therapies and future directions in pulmonary arterial hypertension
V Gurtu, ED Michelakis - Canadian Journal of Cardiology, 2015 - Elsevier
Pulmonary arterial hypertension (PAH) is a complex obliterative vascular disease. It remains
deadly despite an explosion of basic research over the past 20 years that identified myriads …
deadly despite an explosion of basic research over the past 20 years that identified myriads …
New trial designs and potential therapies for pulmonary artery hypertension
M Gomberg-Maitland, TM Bull, R Saggar… - Journal of the American …, 2013 - jacc.org
A greater understanding of the epidemiology, pathogenesis, and pathophysiology of
pulmonary artery hypertension (PAH) has led to significant advances, but the disease …
pulmonary artery hypertension (PAH) has led to significant advances, but the disease …
Advances in the management of pulmonary arterial hypertension
H Deshwal, T Weinstein… - Journal of Investigative …, 2021 - journals.sagepub.com
The management of pulmonary arterial hypertension (PAH) has significantly evolved over
the last decades in the wake of more sensitive diagnostics and specialized clinical programs …
the last decades in the wake of more sensitive diagnostics and specialized clinical programs …
Management of pulmonary arterial hypertension
JD Mayeux, IZ Pan, J Dechand, JA Jacobs… - Current cardiovascular …, 2021 - Springer
Abstract Purpose of Review This review focuses on the therapeutic management and
individualized approach to Group 1 pulmonary arterial hypertension (PAH), utilizing Food …
individualized approach to Group 1 pulmonary arterial hypertension (PAH), utilizing Food …
Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies
SL Archer, EK Weir, MR Wilkins - Circulation, 2010 - Am Heart Assoc
Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary arterial
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …