The administration of cyproterone acetate (CPA) and estradiol is a common regimen used
by male-to-female transsexuals (transwoman) to adjust their body to their gender identity …

Transsexualism is defined as a strong conviction of belonging to the opposite sex in
individuals without any physical intersex condition. Cross-sex hormone therapy is an …

Background: Gender-affirming hormone therapy is critical to the management of transgender
persons. Cyproterone acetate (CPA) is a synthetic, progesterone-like compound commonly …

Sex hormones have been proposed as a possible risk factor for the development and growth
of meningiomas. Hormonal therapy plays a fundamental role in the treatment of male‐to …

Transsexual patients are routinely treated with sex hormone therapy, which may be a risk
factor for meningiomas, although the data are largely inconclusive. Here we describe a male …

Benign brain tumours may be hormone sensitive. To induce physical characteristics of the
desired gender, transgender individuals often receive cross-sex hormone treatment …

Growth of a Meningioma in a Transsexual Patient after Estrogen–Progestin Therapy Page 1
correspondence n engl j med 357;23 www.nejm.org december 6, 2007 2411 Dr. Farooki …

Objective To assess the risk of meningioma associated with use of high dose cyproterone
acetate, a progestogen indicated for clinical hyperandrogenism. Design Observational …

The role of sex hormones in the pathogenesis of meningioma is an area of ongoing
investigation. Here we describe the third published case of a de novo World Health …

WHAT IS ALREADY KNOWN ON THIS SUBJECT• Information from the spontaneous
reporting system raised the hypothesis of an increased risk of meningioma in patients …