Hesperidin Inhibits Inflammatory Response Induced by Aeromonas hydrophila Infection and Alters CD4+/CD8+ T Cell Ratio

ASA Abuelsaad, G Allam… - Mediators of …, 2014 - Wiley Online Library
Background. Aeromonas hydrophila is an opportunistic bacterial pathogen that is associated
with a number of human diseases. Hesperidin (HES) has been reported to exert antioxidant …

Antimicrobial and immunomodulating activities of hesperidin and ellagic acid against diarrheic Aeromonas hydrophila in a murine model

ASA Abuelsaad, I Mohamed, G Allam, AA Al-Solumani - Life sciences, 2013 - Elsevier
Aims The present study is designed to evaluate the in vitro and in vivo bactericidal and
immunomodulating activities of hesperidin (HES) and ellagic acid (EA) against Aeromonas …

In vivo and in vitro evaluation of the protective effects of hesperidin in lipopolysaccharide-induced inflammation and cytotoxicity of cell

R Al-Rikabi, H Al-Shmgani, YH Dewir, S El-Hendawy - Molecules, 2020 - mdpi.com
(1) Background: Plant flavonoids are efficient in preventing and treating various diseases.
This study aimed to evaluate the ability of hesperidin, a flavonoid found in citrus fruits, in …

Hesperidin prevents lipopolysaccharide-induced endotoxicity in rats

SO Rotimi, GE Bankole, IB Adelani… - Immunopharmacology …, 2016 - Taylor & Francis
Context: Lipopolysaccharide (LPS) is a major trigger of septic shock resulting in multiple
organ damage through excessive stimulation of the host's immune cells resulting in the …

Evaluation of hesperidin protective effect on lipopolysaccharide-induced inflammation and lipid peroxidation in BALB/C mail mice

RH Al-Rikabi, HS Al-Shmgani - Research Journal of Pharmacy …, 2018 - indianjournals.com
Hesperidin is a flavonoid found mainly in citric, has been shown to reduce inflammation. In
the present study, we have tested the ability of hesperidin to inhibit lipopolysaccharide (LPS) …

The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro

CC Yeh, SJ Kao, CC Lin, SD Wang, CJ Liu, ST Kao - Life sciences, 2007 - Elsevier
To investigate the modulation of lung local immune responses of hesperidin (HES) on the
acute lung inflammation induced by LPS in vivo. Mice were challenged with intratracheal …

[HTML][HTML] Ephedrine hydrochloride protects mice from staphylococcus aureus-induced peritonitis

W He, J Ma, Y Chen, X Jiang, Y Wang… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Staphylococcus aureus is a Gram-positive (G+) bacterium that causes a wide range of
diseases in humans and livestock. Therefore, the development of innovative and effective …

Protective effects of hesperetin on lipopolysaccharide-induced acute lung injury by targeting MD2

J Ye, M Guan, Y Lu, D Zhang, C Li, Y Li… - European journal of …, 2019 - Elsevier
Inflammation plays an important role in acute lung injury (ALI). Hesperetin (HES), a natural
flavanone and an aglycone of hesperidin, has established potent anti-inflammatory activity …

A comparative study of hesperetin, hesperidin and hesperidin glucoside: Antioxidant, anti-inflammatory, and antibacterial activities in vitro

SS Choi, SH Lee, KA Lee - Antioxidants, 2022 - mdpi.com
The antioxidant, anti-inflammatory and antibacterial activities of hesperetin, hesperidin and
hesperidin glucoside with different solubility were compared in vitro. Hesperetin was …

Hesperidin suppresses ovalbumin-induced airway inflammation in a mouse allergic asthma model

D Wei, X Ci, X Chu, M Wei, S Hua, X Deng - Inflammation, 2012 - Springer
Hesperidin, a flavanone glycoside comprised of the flavanone hesperetin and the
disaccharide rutinose, is a plentiful and inexpensive by-product of citrus cultivation. It has …