Superoxide dismutases (SODs) catalyze the de toxification of superoxide. SODs therefore
acquired great importance as O2 became prevalent following the evolution of oxygenic …

Fe and Mn are both entrained to the same chemical reaction in apparently superimposable
superoxide dismutase (SOD) proteins. However, neither Fe-substituted MnSOD nor Mn …

Publisher Summary The presence of oxygen in the environment presents both advantages
and threat to all forms of life. The use of oxygen as a final electron acceptor provides more …

Superoxide dismutases are enzymes that defend against oxidative stress through
decomposition of superoxide radical. Escherichia coli contains two highly homologous …

We propose that the apparent catalytic inactivity of Mn-and Fe-substituted superoxide
dismutases (SODs) reflects E° s that are either lower (Fe-sub-(Mn) SOD) or higher (Mn-sub …

The manganese and iron SODs (superoxide dismutases) form a superfamily of closely
related antioxidant defence metalloenzymes. MnSOD requires Mn (not Fe) for activity …

The field of free radical biology originated with the discovery of superoxide dismutase (SOD)
in 1969. Over the last 5 decades, a plethora of research has been performed in species …

The discovery of superoxide dismutases (SODs), which convert superoxide radicals to
molecular oxygen and hydrogen peroxide, has been termed the most important discovery of …

Protection from oxidative damage is sufficiently important that biology has evolved three
independent enzymes for hastening superoxide dismutation: the Cu-and Zn-containing …

The past two decades have witnessed an explosion in our understanding of oxygen toxicity.
The discovery of superoxide dismutases (SODs)(EC. 1.15. 1.1), which specifically catalyze …