The present study was conducted to investigate protein levels of inducible NO synthase
(iNOS) and cayclooxygenase-2 (COX-2) in human colon cancer tissues. Significant increase …

Abstract Cyclooxygenase-2 (COX-2) enzyme is believed to play a role in tumor
angiogenesis, differentiation, and apoptosis. The inducible isoform of nitric oxide synthase …

An increase in the expression and activity of both inducible nitric oxide synthase (iNOS) and
cyclooxygenase-2 (COX-2) has been shown in several types of human tumors. A large body …

Purpose: Up-regulation of both inducible nitric oxide synthase (iNOS) and cyclooxygenase-2
(COX-2) enzymes has been reported in colorectal cancer. We aimed at evaluating the …

Abstract Cyclooxygenase (COX)‐2 has been suggested to play an important role in colon
carcinogenesis. We found that the COX‐2 selective inhibitor, nimesulide, reduces …

Background: The expression of inducible nitric oxide synthase (iNOS) has been reported to
be altered in a number of tumours, but its role in tumour biology is still unclear. Methods …

To determine the effect of nitric oxide (NO) on the cyclooxygenase-2 (COX-2) regulation in
colon cancer cell lines we used the physiological NO donor GSNO. The proximal 6.6 kb of …

Significance of expression of cytokine induced nitric oxide synthase (iNOS) in colorectal
carcinoma remains controversial. The aim of the current study was to elucidate the …

Despite recognition of the devastating malignant potential of the pancreatic ductal cancer,
the exact pathophysiological events contributing to tumor growth remain to be elucidated …

The overexpression of cyclooxygenase‐2 (COX‐2) and inducible nitric oxide synthase
(iNOS) has been previously reported in head and neck squamous cell carcinoma (HNSCC) …