Use of the Rockwood Clinical Frailty Scale in patients with advanced hepatopancreaticobiliary malignancies

D Shah, ZA Kapacee, A Lamarca… - Expert Review of …, 2022 - Taylor & Francis
Background Co-existing frailty in older patients with hepatopancreaticobiliary (HPB)
malignancies is common. This study assessed the relationship between the Rockwood …

[HTML][HTML] The prevalence and the impact of frailty in hepato-biliary pancreatic cancers: a systematic review and meta-analysis

K Komici, M Cappuccio, A Scacchi, R Vaschetti… - Journal of Clinical …, 2022 - mdpi.com
Background: Frailty has been associated with increased mortality among hepatobiliary
pancreatic (HBP) cancer patients. Nevertheless, estimates of frailty prevalence in HBP …

[HTML][HTML] Frailty assessment tools and geriatric assessment in older patients with hepatobiliary and pancreatic malignancies

S Rostoft, B van Leeuwen - European Journal of Surgical Oncology, 2021 - Elsevier
Background The majority of patients with hepatobiliary and pancreatic (HBP) malignancies
are older than 65 years. Due to the heterogeneity of this older population, decisions …

Utility of the modified frailty index in predicting toxicity and cancer outcomes for older adults with advanced pancreatic cancer receiving first-line palliative …

R Rittberg, H Zhang, P Lambert, R Kudlovich… - Journal of Geriatric …, 2021 - Elsevier
Background Pancreatic cancer primarily affects older adults and is associated with a high
morbidity and mortality. Identifying frail patients with advanced pancreatic cancer (APC) …

Development of a health data derived frailty index as a predictor of adverse outcomes in older patients with pancreatic cancer

JP Negrete-Najar, M Sehovic, MG Rodriquenz… - Journal of Geriatric …, 2022 - Elsevier
Pancreatic cancer is a prevalent disease among older adults. Well-selected patients, based
on a geriatric assessment for risk stratification, could be good candidates for chemotherapy …

Impact of geriatric assessment (GA) based frailty index (CARE-Frailty Index) on mortality and treatment-related toxicity among older adults with gastrointestinal (GI) …

S Giri, M Al-Obaidi, C Harmon, C Dai, CY Smith… - 2021 - ascopubs.org
12046 Background: Older adults with cancer are at increased risk of treatment-related
toxicity and mortality. A comprehensive geriatric assessment (GA) may uncover aging …

Patient‐reported geriatric assessment‐based frailty index among older adults with gastrointestinal malignancies

S Giri, M Al‐Obaidi, C Harmon, D Clark… - Journal of the …, 2023 - Wiley Online Library
Background Older adults with cancer are at increased risk of treatment‐related toxicities and
excess mortality. We evaluated whether a patient‐reported geriatric assessment (GA) based …

Differences in pretreatment frailty across gastrointestinal cancers in older adults: Results from the cancer and aging resilience evaluation registry

S Arora, ME Fowler, C Harmon, M Al-Obaidi… - JCO Oncology …, 2022 - ascopubs.org
PURPOSE: Frailty predicts poor outcomes in older adults with cancer, but how it differs
between different cancer types is unknown. We examined differences in pretreatment frailty …

Validation of a frailty index in older cancer patients with solid tumours

AL McCarthy, NM Peel, KM Gillespie, R Berry… - BMC cancer, 2018 - Springer
Background Frailty is an indicator of physiological reserve in older people. In non-cancer
settings, frailty indices are reliable predictors of adverse health outcomes. The aims of this …

Electronic Frailty Index: A risk stratification tool for survival and health care outcomes in veterans with colorectal cancer.

H Zhu, J Razjouyan, S Yarlagadda, A Naik, YH Sada - 2022 - ascopubs.org
375 Background: Frailty reflects decreased physiologic reserve and subsequent increased
vulnerability to stress. Frailty has been associated with poor health outcomes in patients with …