[HTML][HTML] Suppression of inflammation-induced lung cancer cells proliferation and metastasis by exiguaflavanone A and exiguaflavanone B from Sophora exigua root …

P Arjsri, K Srisawad, W Semmarath… - Frontiers in …, 2023 - frontiersin.org
Objective: Non-small cell lung cancer (NSCLC) is recognized for its aggressive nature and
propensity for high rates of metastasis. The NLRP3 inflammasome pathway plays a vital role …

Scutellaria baicalensis pith-decayed root inhibits macrophage-related inflammation through the NF-κB/NLRP3 pathway to alleviate LPS-induced acute lung injury

F Zhang, C Ke, Z Zhou, K Xu, Y Wang, Y Liu… - Planta Medica, 2023 - thieme-connect.com
Acute lung injury (ALI) is one of the representative “lung heat syndromes” in traditional
Chinese medicine (TCM). Scutellaria baicalensis is an herbal medicine used in TCM for …

[HTML][HTML] Qingwenzhike Prescription Alleviates Acute Lung Injury Induced by LPS via Inhibiting TLR4/NF-kB Pathway and NLRP3 Inflammasome Activation

C Zhang, X Wang, C Wang, C He, Q Ma, J Li… - Frontiers in …, 2021 - frontiersin.org
Background: Acute lung injury (ALI) is characterized by dysfunction of the alveolar epithelial
membrane caused by acute inflammation and tissue injury. Qingwenzhike (QWZK) …

Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264. 7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO …

C Guo, L Yang, J Luo, C Zhang, Y Xia, T Ma… - International …, 2016 - Elsevier
Sophoraflavanone G (SG), a prenylated flavonoid from Sophora alopecuroides, has been
reported to have many pharmacological activities including anti-inflammation. However, the …

[HTML][HTML] Dehydroisohispanolone as a promising NLRP3 inhibitor agent: bioevaluation and molecular docking

L González-Cofrade, I Cuadrado, Á Amesty… - Pharmaceuticals, 2022 - mdpi.com
Dehydroisohispanolone (DIH), is a labdane diterpene that has exhibited anti-inflammatory
activity via inhibition of NF-κB activation, although its potential effects on inflammasome …

[HTML][HTML] Targeting spike glycoprotein S1 mediated by NLRP3 inflammasome machinery and the cytokine releases in A549 lung epithelial cells by nanocurcumin

C Chittasupho, K Srisawad, P Arjsri, R Phongpradist… - Pharmaceuticals, 2023 - mdpi.com
Chronic inflammation and tissue damage can result from uncontrolled inflammation during
SARS-CoV-2 or COVID-19 infections, leading to post-acute COVID conditions or long …

[HTML][HTML] Yupingfeng San Inhibits NLRP3 Inflammasome to Attenuate the Inflammatory Response in Asthma Mice

X Liu, J Shen, D Fan, X Qiu, Q Guo, K Zheng… - Frontiers in …, 2017 - frontiersin.org
Yupingfeng San (YPFS) is a representative Traditional Chinese Medicine (TCM) formula
with accepted therapeutic effect on Asthma. However, its action mechanism is still obscure …

[HTML][HTML] Saponins from Aesculus wilsonii seeds exert anti-inflammatory activity through the suppression of NF-κB and NLRP3 pathway

H Li, H Cao, J Ruan, Y Wu, D Yang, Q Gao… - Arabian Journal of …, 2023 - Elsevier
The seeds of Aesculus wilsonii were reported to be rich in saponins and have anti-
inflammatory activity. However, the phytochemistry investigation of its saponins is not clear …

Anti-inflammatory effect of the six compounds isolated from Nauclea officinalis Pierrc ex Pitard, and molecular mechanism of strictosamide via suppressing the NF-κB …

DY Li, JQ Chen, JQ Ye, XT Zhai, J Song… - Journal of …, 2017 - Elsevier
Abstract Ethnopharmacological relevance Nauclea officinalis Pierrc ex Pitard. is a Chinese
medicinal herb that contains high level of alkaloids which is the most abundant and active …

Isorhamnetin and hyperoside derived from water dropwort inhibits inflammasome activation

H Ahn, GS Lee - Phytomedicine, 2017 - Elsevier
Abstract Background Water dropwort (Oenanthe javanica), an umbelliferous plant, has been
reported as hypolipidemic, antiplatelet, antitumor, or immune-stimulating agents and it has …