An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model
The Zika virus (ZIKV) outbreak in the Americas and South Pacific poses a significant burden
on human health because of ZIKV's neurotropic effects in the course of fetal development …
on human health because of ZIKV's neurotropic effects in the course of fetal development …
A ferritin nanoparticle-based zika virus vaccine candidate induces robust humoral and cellular immune responses and protects mice from lethal virus challenge
The severe consequences of the Zika virus (ZIKV) infections resulting in congenital Zika
syndrome in infants and the autoimmune Guillain–Barre syndrome in adults warrant the …
syndrome in infants and the autoimmune Guillain–Barre syndrome in adults warrant the …
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination
Zika virus (ZIKV) has recently emerged as a pandemic associated with severe
neuropathology in newborns and adults. There are no ZIKV-specific treatments or …
neuropathology in newborns and adults. There are no ZIKV-specific treatments or …
Development of a potent Zika virus vaccine using self-amplifying messenger RNA
K Luisi, KM Morabito, KE Burgomaster, M Sharma… - Science …, 2020 - science.org
Zika virus (ZIKV) is the cause of a pandemic associated with microcephaly in newborns and
Guillain-Barre syndrome in adults. Currently, there are no available treatments or vaccines …
Guillain-Barre syndrome in adults. Currently, there are no available treatments or vaccines …
[HTML][HTML] Modified mRNA vaccines protect against Zika virus infection
The emergence of ZIKV infection has prompted a global effort to develop safe and effective
vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine …
vaccines. We engineered a lipid nanoparticle (LNP) encapsulated modified mRNA vaccine …
An optimized messenger RNA vaccine candidate protects non-human primates from Zika virus infection
B Bollman, N Nunna, K Bahl, CJ Hsiao, H Bennett… - npj Vaccines, 2023 - nature.com
Zika virus (ZIKV), an arbovirus transmitted by mosquitoes, was identified as a cause of
congenital disease during a major outbreak in the Americas in 2016. Vaccine design …
congenital disease during a major outbreak in the Americas in 2016. Vaccine design …
Virus-like particles that display Zika virus envelope protein domain III induce potent neutralizing immune responses in mice
Several Zika virus (ZIKV) vaccine candidates have recently been described which use
inactivated whole virus, DNA or RNA that express the virus' Envelope (E) glycoprotein as the …
inactivated whole virus, DNA or RNA that express the virus' Envelope (E) glycoprotein as the …
mRNA vaccine protects against zika virus
LG Medina-Magües, J Gergen, E Jasny, B Petsch… - Vaccines, 2021 - mdpi.com
Zika virus (ZIKV), a mosquito-borne flavivirus, has recently triggered global concern due to
severe health complications. In 2015, a large ZIKV outbreak occurred in the Americas and …
severe health complications. In 2015, a large ZIKV outbreak occurred in the Americas and …
CD8+ T cells mediate protection against Zika virus induced by an NS3-based vaccine
A Elong Ngono, T Syed, AV Nguyen… - Science …, 2020 - science.org
Zika virus (ZIKV) is associated with congenital malformations in infants born to infected
mothers, and with Guillain-Barré syndrome in infected adults. Development of ZIKV vaccines …
mothers, and with Guillain-Barré syndrome in infected adults. Development of ZIKV vaccines …
Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality
S Maciejewski, TJ Ruckwardt, KM Morabito… - Science translational …, 2020 - science.org
The emergence of Zika virus (ZIKV) in the Americas stimulated the development of multiple
ZIKV vaccine candidates. We previously developed two related DNA vaccine candidates …
ZIKV vaccine candidates. We previously developed two related DNA vaccine candidates …